نتایج جستجو برای: clinical trial

تعداد نتایج: 1365604  

Journal: :Biometrical journal. Biometrische Zeitschrift 2011
Roger Koenker

The Laplace likelihood method for estimating linear conditional quantile functions with right censored data proposed by Bottai and Zhang (2010) is demonstrated to be highly non-robust.

Journal: :Annals of statistics 2003
Mark J VAN DER Laan Nicholas P Jewell

We study nonparametric estimation with two types of data structures. In the first data structure n i.i.d. copies of (C, N(C)) are observed, where N is a finite state counting process jumping at time-variables of interest and C a random monitoring time. In the second data structure n i.i.d. copies of (C ∧ T, I (T ≤ C), N(C ∧ T)) are observed, where N is a counting process with a final jump at ti...

Journal: :The international journal of biostatistics 2008
Debashis Ghosh

In the analysis of dependence of bivariate correlated failure time data, a popular model is a gamma frailty model proposed by Clayton and Oakes. An alternative approach is using a Plackett distribution, whose dependence parameter has a very appealing odds ratio interpretation for dependence between the two failure times. In this article, we develop novel semiparametric estimation and inference ...

Journal: :Lifetime data analysis 1999
W Pan R Chappell

We show that under reasonable conditions the nonparametric maximum likelihood estimate (NPMLE) of the distribution function from left-truncated and case 1 interval-censored data is inconsistent, in contrast to the consistency properties of the NPMLE from only left-truncated data or only interval-censored data. However, the conditional NPMLE is shown to be consistent. Numerical examples are prov...

2015
Malcolm Macleod

.....in which Professor Benchie, an established super-subspeciality clinician who spends most of his time performing laboratory research, profers advice toAthena, an enthusiastic early career physician who, although she spent summers in the lab as a medical student, is just finishing a research fellowship that included a course in clinical research and wonders whether she would prefer to devote...

Journal: :Journal of chronic diseases 1959
J P BULL

Journal: :Lifetime data analysis 2016
Yang Li Xin He Haiying Wang Jianguo Sun

Longitudinal data occur in many fields such as the medical follow-up studies that involve repeated measurements. For their analysis, most existing approaches assume that the observation or follow-up times are independent of the response process either completely or given some covariates. In practice, it is apparent that this may not be true. In this paper, we present a joint analysis approach t...

Journal: :Munchener medizinische Wochenschrift 1959
W TRUMMERT

Journal: :Test 2009
Gang Li Xuyang Lu

We provide a review on the empirical likelihood method for regression type inference problems. The regression models considered in this review include parametric, semiparametric and nonparametric models. Both missing data and censored data are accommodated.

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