نتایج جستجو برای: clinical outcome
تعداد نتایج: 1407456 فیلتر نتایج به سال:
OBJECTIVE To determine general practitioners' attitudes to medical audit and to establish what initiatives are already being undertaken; to define future ideas for audit and perceived difficulties in implementing audit in primary care. DESIGN Analysis of responses to a self administered postal questionnaire. SETTING Urban conurbation with a population of about 750,000. PARTICIPANTS 386 ge...
OBJECTIVE To determine the medium-term outcome of Ahmed implants inserted through a needle tract at 5 mm from limbus that eliminates the need for a donor scleral graft. METHODS A retrospective case series of 19 patients undergoing Ahmed implant surgery for refractory glaucoma with a mean follow-up of 12 months. Primary outcome measures included control of intraocular pressure after surgery. S...
This paper explores the concept of maintenance physiotherapy. Firstly, a consensus definition of maintenance physiotherapy is proposed following consultation with 11 senior physiotherapists throughout Australasia. This consensus definition is compared retrospectively with a definition of maintenance physiotherapy given in response to interview of 91 physiotherapists treating non-catastrophicall...
AIM To assess the development and implementation of the Integrated Rapid Assessment and Treatment (IRAT) pathway for the management of patients with fecal incontinence and measure its impact on patients' care. METHODS Patients referred to the colorectal unit in our hospital for the management of faecal incontinence were randomised to either the Standard Care pathway or the newly developed IRA...
OBJECTIVE Infant colic (IC) is defined as recurrent and prolonged crying without an obvious cause or evidence of failure to thrive or illness. It is a common problem with a prevalence of 5%-25%. The unknown aetiology results in a wide variety in interventions and use of heterogeneous outcome measures across therapeutic trials. Our aim was to develop a core outcome set (COS) for IC to facilitate...
BACKGROUND Developing valid and reliable patient-reported outcome measures (PROMs) is a critical step in promoting patient-centered health care, a national priority in the U.S. Small populations or rare diseases often pose difficulties in developing PROMs using traditional methods due to small samples. METHODS To overcome the small sample size challenge while maintaining psychometric soundnes...
BACKGROUND AND PURPOSE Our purpose was to determine whether clinical prediction rules could be derived from current stroke outcome research. SUMMARY OF REPORT We reviewed 92 articles on stroke outcome research to determine their suitability for implementation as a clinical prediction rule. Methodological problems in many of these studies made implementation of their results as a clinical pred...
INTRODUCTION No existing patient-reported outcome instrument focuses solely on assessment of varicose veins symptoms that are bothersome to patients. METHODS The VVSymQ® instrument is a five-item patient-reported outcome that assesses symptoms most important to patients with varicose veins (heaviness, achiness, swelling, throbbing and itching). This paper describes how the VVSymQ® instrument ...
OBJECTIVE To assess available evidence on the use of end-points (outcome measures) in clinical trials in systemic lupus erythematosus (SLE), as a part of the development of evidence-based recommendations for points to consider in clinical trials in SLE. METHODS The European League Against Rheumatism (EULAR) Task Force on SLE comprised 19 specialists, a clinical epidemiologist and a research f...
Gene-expression signature-based disease classification and clinical outcome prediction has not been widely introduced in clinical medicine as initially expected, mainly due to the lack of extensive validation needed for its clinical deployment. Obstacles include variable measurement in microarray assay, inconsistent assay platform, analytical requirement for comparable pair of training and test...
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