Short-wavelength-sensitive (SWS) resolution acuity has been reported to be limited by the density of the responding ganglion cells for people without appreciable age-related lenticular change. This study measured the robustness of SWS-cone acuity and contrast sensitivity (CS) to simulated lens yellowing and opacification. Resolution acuity at 8 deg eccentricity proved robust to significant amou...

The visual acuities of 36 young amblyopes were determined by (a) conventional recognition tests (near and distance) and (b) an adapted grating acuity card procedure. Considerable agreement between the estimates of acuity obtained with each method was demonstrated, which was generally less than, or equal to, the mean difference between adjacent Snellen lines (4.5 c deg-1). Estimates of grating a...

AIM To provide information on the use of vision tests in clinical decision making about cataract surgery in the UK. METHOD A questionnaire survey was mailed to 703 consultant ophthalmologists. RESULTS A response rate of 70% was obtained. Monocular distance visual acuity was the only visual function that was tested routinely by all surgeons. Supplementary use of contrast sensitivity and glar...

PURPOSE To evaluate interobserver test-retest reliability of the Teller Acuity Card procedure for assessment of grating acuity at ages 1, 2, 3.5, 4.5, and 5.5 years, for HOTV letter acuity at 3.5 and 4.5 years, and for Early-Treatment Diabetic Retinopathy Study (ETDRS) letter acuity at 5.5 years in the multicenter study of Cryotherapy for Retinopathy of Prematurity (CRYO-ROP). METHODS Subject...

Purpose: This study set out to examine the impact of surgical treatment senile cataract on visual acuity and quality life in patients operated a public teaching hospital. Methods: Prospective including aged over 60 years with clinical indications for surgery treated at medical residency service. The National Eye Institute Visual Function Questionnaire 25 was applied. Corrected distance measured...

This study investigated the possible therapeutic effects of oral rifampin on patients with acute Central Serous Chorioretinopathy (CSC). clinical trial was a randomized placebo-controlled, double-masked research involving 30 CSC. The were randomly assigned into two groups, one receiving 600 mg once day for month and another being matched placebo group. Best Corrected Visual Acuity (BCVA), subre...

IMPORTANCE Establishing the natural history of G11778A Leber hereditary optic neuropathy (LHON) is important to determine the optimal end points to assess the safety and efficacy of a planned gene therapy trial. OBJECTIVE To use the results of the present natural history study of patients with G11778A LHON to plan a gene therapy clinical trial that will use allotopic expression by delivering a ...

PURPOSE Infantile nystagmus syndrome (INS) can be idiopathic or associated with ocular or systemic disease. The ocular oscillation of INS directly contributes to loss of visual acuity. In this study, visual acuity development in patients with INS was examined. METHODS Children with INS were classified as having idiopathic INS (n = 84) or INS with an associated sensory deficit: INS and albinis...