Optical clearing is emerging as a popular approach particularly for studies in neuroscience. However the use of corrosive clearing solutions typically requires sophisticated objectives or extreme care with optical components chosen for single- or multi-photon imaging. In contrast to the use of complex, custom-made microscope objectives, we show that the use of a corrected multimode fibre (MMF) ...

Market clearing in restructured power systems is mostly implemented through an offer-based setting with the goal of maximizing social welfare. This approach leads to sound results from an economic viewpoint when generation offers reflect true production costs. However, offers may significantly differ from actual costs in practice, thus yielding undesired distortion. Under a marginal pricing sch...

Optical clearing, in combination with recently developed optical imaging techniques, enables visualization and acquisition of high-resolution, three-dimensional images of biological structures deep within the tissue. Many different approaches can be used to reduce light absorption and scattering within the tissue, but there is a paucity of research on the quantification of clearing efficacy. Wi...

In [1] the use of VCG in matching markets is motivated by saying that in order to compute market clearing prices in a matching market, the auctioneer needs to know the true valuations of the bidders. Hence VCG and corresponding personalized prices are proposed as an incentive compatible mechanism. The same line of argument pops up in several lecture sheets and other documents related to courses...

1. In rats in a variety of nutritional states, the adipose tissue clearing factor lipase activity is strongly, positively correlated with fat-cell triglyceride fatty acid uptake. 2. In the same animals, muscle clearing factor lipase activity is inversely correlated with the activity of the enzyme in adipose tissue and with the plasma insulin concentration. 3. In starved animals that are given g...

Optical emission computed tomography (optical-ECT) is a technique for imaging the three-dimensional (3D) distribution of fluorescent probes in biological tissue specimens with high contrast and spatial resolution. In optical-ECT, functional information can be imaged by (i) systemic application of functional labels (e.g. fluorophore labelled proteins) and/or (ii) endogenous expression of fluores...

In this paper, we evaluate the Analysis of Competing Hypotheses (ACH) method using a normative Bayesian probabilistic framework. We describe the ACH method and present an example of how to use it to structure an analytic problem. We then show how to represent the same analytic problem using Bayesian networks and compare the result with that using the ACH method. We discuss how Bayesian networks...

Tissue clearing methods promise to provide exquisite three-dimensional imaging information; however, there is a need for simplified methods for lower resource settings and for non-fluorescence based phenotyping to enable light microscopic imaging modalities. Here we describe the simplified CLARITY method (SCM) for tissue clearing that preserves epitopes of interest. We imaged the resulting tiss...

The market clearing prices in deregulated electricity markets are volatile. Good market clearing price forecasting will help producers and consumers to prepare their corresponding bidding strategies so as to maximize their profits. Market clearing price prediction is a difficult task since bidding strategies used by market participants are complicated and various uncertainties interact in an in...

Cerebro vascular CO2 Reactivity of the Fast and Slow Clearing Compartments • Regional cerebral blood flow measurements have been made at two levels of Paco, using the clearance of Xenon injected into the internal carotid artery. Specific and percent changes in blood flow per mm Hg change in Paco, (CO2 reactivity) have been calculated for the fast and slow clearing tissue (Ff and Fs) and F initi...