نتایج جستجو برای: circumsporozoite protein

تعداد نتایج: 1234774  

2013
Nagesh R. Aragam Kelly M. Thayer Nabi Nge Irving Hoffman Francis Martinson Debbie Kamwendo Feng-Chang Lin Colin Sutherland Jeffrey A. Bailey Jonathan J. Juliano

Circumsporozoite protein (CS) is a leading vaccine antigen for falciparum malaria, but is highly polymorphic in natural parasite populations. The factors driving this diversity are unclear, but non-random assortment of the T cell epitopes TH2 and TH3 has been observed in a Kenyan parasite population. The recent publication of the crystal structure of the variable C terminal region of the protei...

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