The circulatory system of Drosophilamelanogaster represents an easily amenable genetic model whose analysis at different levels, i.e., from single molecules up to functional anatomy, has provided new insights into general aspects of cardiogenesis, heart physiology and cardiac aging, to name a few examples. In recent years, the Drosophila heart has also attracted the attention of researchers in ...

This research presents a dual-perspective, or bipartite view of teleology (i.e . purpose) and uses it to criticize qualitative models of cardiovascular systems in a manner that highlights the relationships between circulatory topology, behavior and function . The Bipartite Teleology Model (BTM) attributes 'purposefulness' to both steady-state and regulatory behavior thereby providing a split-le...

Different combinations of the artero-ventricular coupling design (numerical, physical and hybrid) and the arterial system structure (four-element standard, simplified, modified and three-element three-lump "ladder" Windkessel) have been applied in an open loop circulatory model to test their influence on selected ventricular and circulatory variables. Numerical investigations have shown that a ...

Indonesia's scientific literacy ability is low with a score of 389. This can indicate the critical thinking skills junior high school students. To improve be done by innovating learning tools. For this reason, research was conducted using R&D method to develop UKBM which help students achieve mastery. part In study, prepared based on Problem Based Learning (PBL) physics human circulatory sy...

Cholesterol is a vital structural and functional molecule in the human body that is only slightly soluble in water and therefore does not easily travels by itself in the bloodstream. To enable cholesterol's targeted delivery to cells and tissues, it is encapsulated by different fractions of lipoproteins, complex particles containing both proteins and lipids. Maintaining cholesterol homeostasis ...

Numerous electrical analog models of the circulatory system have been proposed. However, conventional models are either too simple, focusing exclusively on heart function, or overly complex, characterizing arteries in excessive detail. The vessel beds, which comprise arteries, capillaries and veins, are well known to be responsible for most of the pressure drop in blood pressure and to dominate...

Ohio State University researchers have made a leap forward in disease research by creating an eraser sized human "brain" in a petri dish1. Although lacking a circulatory system their brain model includes spinal cord, cortex, midbrain, brain stem, and even the beginnings of an eye- aiding in the effectiveness of research on complex neurological disease. To create their new brain model, the resea...

Abstract Background Congenital malformations (CMs) were the second cause of death in infants under age 1 year North America and Europe 2017, behind perinatal causes.Of CMs, those circulatory system (MCSs) most lethal. Studies Brazil, England have reported higher mortality from MCS presence prematurity, non-white skin color newborn, asphyxia, low birthweigth, advanced maternal age, education lev...