Background and purpose. Arachidonic acid (AA) and its derivatives are important modulators of cellular signalling. The transient receptor potential cation channel subfamily A, member 1 (TRPA1) is a cation channel with important functions in mediating cellular responses to noxious stimuli and inflammation. There is limited information about the interactions between AA itself and TRPA1, so we inv...

AIMS To investigate the antimicrobial activity of various natural products against Clostridium difficile in vitro. METHODS AND RESULTS The antibacterial activity of 20 natural products was determined by the agar well diffusion and broth microdilution assays against four C. difficile strains, three comparator organisms and four gastrointestinal commensal organisms. Of the raw natural products,...

BACKGROUND/AIM Biofilm on urinary catheters results in persistent infections that are resistant to antibiotics. In this study, phytochemicals were assessed as alternative antimicrobials in preventing and inactivating E. coli biofilm on urinary catheters. MATERIALS AND METHODS Biofilm prevention was tested using catheter fragments inoculated with E. coli and treated with trans- cinnamaldehyde,...

Common food irritants elicit oral heat or cool sensations via actions at thermosensitive transient receptor potential (TRP) channels. We used a half-tongue, 2-alternative forced-choice procedure coupled with bilateral pain intensity ratings to investigate irritant effects on heat and cold pain. The method was validated in a bilateral thermal difference detection task. Capsaicin, mustard oil, an...

The stability of a bimetallic Au–Pd/TiO2 catalyst was examined in a packed bed microreactor for the oxidation of cinnamyl alcohol dissolved in toluene. The catalyst was prepared by co-impregnation with a Au–Pd weight ratio of 1 : 19. Experiments were performed at 80–120 °C, oxygen concentration 0–100% and total pressure 4 bara. Principal products observed were cinnamaldehyde, 3-phenyl-1-propano...

Nanhai No. 1, a shipwreck in the Southern Song Dynasty, China, has history of more than 800 years. It was salvaged 2007 and is now on display Guangdong Maritime Silk Road Museum. Due to fact that hull wooden cultural relic exposed air, biological corrosion biodegradation caused by microorganisms are key problems protection. At present, antimicrobial agent Euxyl® K100 (isothiazolinone) significa...

As a principal compound of cinnamon essential oil, cinnamaldehyde has been used as marker for the quality control and its oil. During HPLC analysis, reaction product was observed in methanol solution reference standard. This isolated identified to be dimethyl acetal based on spectroscopic analysis. Although dimethylacetalization MeOH recorded many literatures, this is first report about normal ...

Schiff bases derived by condensation reaction from cinnamaldehyde and/or -bromocinnamaldehyde and 4-(4-aminophenylsulfonyl)benzenamine are reported and characterized based on elemental analyses, IR, H NMR, C NMR and thermal analysis (TG/DTA). 1 13

Natural antioxidants recently have gained popularity since synthetic ones have toxic and carcinogenic effects. In the present study, effect of temperature (120, 150 and 180°C) and cinnamaldehyde on oxidative stability of several oils (olive, hazelnut and palm oils) and fats (milkfat and butter) was examined. In order to compare the results with the synthetic antioxidant, butylated hydroxy tolue...

Cinnamon is one of the most commonly used spices worldwide. In some Arab countries, cinnamon with other ingredients to relieve bronchospasm and treatment airways-related disorders. current study, GC, GC-MS tracheal relaxant effect comparison were performed using three available types in Saudi Arabia, Cinnamomum verum (Ceylon cinnamon), C. cassia (Chinese cinnamon) loureiroi (Vietnamese cinnamon...