Purpose: The purpose of the current study was to investigate the pathogenesis of visual fatigue in patients after implantable collamer lens (ICL) implantation based on an evaluation of accommodation function. Methods: Thirty patients (12 males and 18 females) with high myopia underwent a toric or non-toric ICL procedure. Accommodation function was tested pre-operatively and 1, 3, and 6 months p...

CASE REPORT We report the clinical features and surgery of a patient with an adenoma of the non-pigmented ciliary epithelium. The adenoma measured 5 × 7 mm. The patient underwent radical ocular surgery consisting of partial iridocyclectomy associated to lamellar sclerouvectomy. DISCUSSION Adenomas of ciliary body can mimic clinically amelanotic melanomas. We present details of the patient's m...

A 25 microliter volume of a 1-% l-epinephrine borate solution applied on the cornea of one eye in 12 monkeys reduced blood flow through the iris and the ciliary body by 59% and 20%, respectively, compared to the untreated control eyes. In the ciliary body the main effect was in the ciliary processes. Blood flow was determined with the labeled microsphere method 1, 4, and 6 hr after application ...

PURPOSE To develop antibodies that selectively recognize each of the alpha 2-adrenergic receptor (AR) subtypes and to determine the expression and localization of these subtypes in the anterior segment of the human eye. METHODS Recent studies have shown that there are three subtypes of the alpha 2-ARs, termed alpha 2-C10 (alpha 2A), alpha 2-C2 (alpha 2B), and alpha 2-C4 (alpha 2C). Polymerase...

A significant number of ciliary disease genes have been found to encode proteins that localise to the basal body. By contrast, a large number of basal-body-associated proteins remain to be characterised. Here, we report the identification of a new basal body protein that is required for ciliogenesis in Drosophila. Dilatory (DILA) is a predicted coiled-coil protein homologous to vertebrate AZI1 ...

Although partial cyclectomy has become an established procedure for the excision of tumours of the ciliary body, difficult clinical decisions are required before embarking on this surgery. Anxiety is caused especially by the uncertainty of unduly disturbing a large malignant lesion and by the surgical risks to the eye in relation to the chances of success in maintaining the integrity of the eye...

Basal bodies are radially symmetric, microtubule-rich structures that nucleate and anchor motile cilia. Ciliary beating produces asymmetric mechanical forces that are resisted by basal bodies. To resist these forces, distinct regions within the basal body ultrastructure and the microtubules themselves must be stable. However, the molecular components that stabilize basal bodies remain poorly de...

Vascular luminal castings of rabbit eyes were microdissected and studied with the scanning electron microscope to delineate the anatomy of the ciliary body microvasculature. We found regional microvascular differences corresponding to well known gross topographical and ultrastructural differences that may indicate regional functional specialization. The major arterial circle of the iris, derive...

Melachronous beating of cilia of epithelial surfaces of most respiratory airways moves the overlying mucous layer in a caudal direction. The molecular mechanisms controlling ciliary beat remain largely unknown. Calcium, an element in its cationic form, is ubiquitous in biological functions and its concentration is critical for ciliary beating. Calmodulin, a calcium-binding protein which regulat...