In covering wounds, efforts should include utilization of the safest and least invasive methods with goals of achieving optimal functional and cosmetic outcome. The recent development of advanced wound healing technology has triggered the use of cells to improve wound healing conditions. The purpose of this review is to provide information on clinically available cell-based treatment options fo...

Medicare skilled nursing facility (SNF) residents with chronic wounds require more resources and have relatively high healthcare expenditures compared to Medicare patients without wounds. A retrospective cohort study was conducted using 2006 Medicare Chronic Condition Warehouse claims data for SNF, inpatient, outpatient hospital, and physician supplier settings along with 2006 Long-Term Care M...

Optical microangiography (OMAG) and Doppler optical microangiography (DOMAG) are two non-invasive techniques capable of determining the tissue microstructural content, microvasculature angiography, and blood flow velocity and direction. These techniques were used to visualize the acute and chronic microvascular and tissue responses upon an injury in vivo. A tissue wound was induced using a 0.5 ...

BACKGROUND Approximately 20% of leg ulcers remain unresponsive to the best conservative standard of care. So far, these patients could either receive conventional skin grafts or had to accept their intractable wound. Skin substitutes from cell culture may represent a promising alternative to heal a major part of these patients on a non-surgical, potentially more cost-effective basis. OBJECTIV...

Introduction: Long-term complications of diabetes leads to physical and mental weakness and reduce their quality of life. One of the complications is the chronic wounds of extremities. Because of its outcome, patient’s adaptation can be reduced. The aim of this study was to compare depression between diabetic patients with and without foot wounds. Materials and methods: The comparati...

Aim: Changes in the pH of chronic wounds can inhibit the optimal activity of various enzymes in the wound environment, thereby delaying wound healing. The aim of the present study is to monitor the effect of limited access dressing (LAD) on the pH on the surface of chronic wounds. Methods: A total of 140 patients with chronic wounds of more than 4 weeks duration were divided into two groups by ...

Tissue assessment for chronic wounds is the basis of wound grading and selection of treatment approaches. While several image processing approaches have been proposed for automatic wound tissue analysis, there has been a shortcoming in these approaches for clinical practices. In particular, seemingly, all previous approaches have assumed only 3 tissue types in the chronic wounds, while these wo...

Vacuum-assisted wound closure (VAC) is a non-invasive, active, wound management therapy exposing the wound bed to local sub-atmospheric negative pressure through a closed system in order to facilitate wound healing. Initially introduced in human medicine for the treatment of chronic wounds, VAC removes fluid from the extra vascular space, improving circulation and enhancing the proliferation of...

As the incidence of diabetes continues to increase in the western world, the prevalence of chronic wounds related to this condition continues to be a major focus of wound care research. Additionally, over 50% of chronic wounds exhibit signs and symptoms that are consistent with localized bacterial biofilms underlying severe infections that contribute to tissue destruction, delayed wound-healing...