Skin aging is an inevitable consequence of human life and accelerated by environmental factors including exposure to ultraviolet radiation pollution. Senescent cells are irreversibly growth arrested accumulate in tissues skin, pre-neoplastic lesions such as naevi at sites age-related pathologies. Actinic keratosis a common skin condition associated with prolonged sun age. If untreated, actinic ...

Background and aim: Adult T cell leukemia/lymphoma (ATLL) is an aggresive malignancy which may occur in human T lymphotropic virus1(HTLV1) infected persons. HTLV1 is endemic in Khorasan with prevalence of 2.3% in general population. Since specific cutaneous manifestations of lymphoma may occur in a significant number of patients, we studied ATLL patients in Mashhad.Mate...

Bachground: Skin lesions are common in type 2 diabetic patients and its association with microvascular complications been reported. Methods: In this study, 1135 type-2 diabetic patients were included and examined by a dermatologist for diabetes mellitus related skin lesions, skin infections and cutaneous complications of the treatment. Smear, culture and biopsy of the lesions were done for defi...

Cutaneous leishmaniasis is acquired from the bite of an infected sand fly and can result in chronic skin lesions that develop within weeks to months after a bite. Local trauma has been implicated as a precipitating event in the development of skin lesions in patients who have been infected with Leishmania species. Here we report a case series and review the literature on patients who developed ...

the clinical and phenotypic features of two siblings (a 12 years old girl and her 7 year old brother) with cockayne syndrome are described. the main problems were mild to moderate mental retardation, dwarfism, clumsy gait, photosensitive skin lesions and progeroid (senile like) appearance. brain ct - scans revealed symmetrical, well defined areas of calcification mainly located at lenticular nu...

Chronic arsenic toxicity (arsenicosis) due to drinking of arsenic contaminated ground water is a major environmental health hazard throughout the world including India. A lot of new information is emerging from extensive research on health effects of chronic arsenic toxicity (CAT) in humans during the last two decades. Available literature has been reviewed to highlight the problem including it...

Mycobacteruim kansasii occasionally causes disseminated infection with poor outcome in immunocompromised patients. We report the first case of disseminated M. kansasii infection associated with multiple skin lesions in a 48-yr-old male with myelodysplastic syndrome. The patient continuously had taken glucocorticoid during 21 months and had multiple skin lesions developed before 9 months without...

we encountered a patient with methylmalonic aciduria associated with skin lesions resembling acrodermatitis enteropathica. this child was being fed with a low-protein diet when the skin disorder developed. a deficiency in plasma levels isoleucine, was confirmed. supplementation of a high-caloric, protein-rich diet led to a prompt improvement of skin lesions. we assume that in our patient the sk...

Systemic lupus erythematous (SLE) is an autoimmune process in which cutaneous lesions occur in majority of patients. This study was conducted to determine the pattern and prevalence of such lesions in SLE in Iranian children infected with SLE. Forty-eight patients, age between 3-16 yrs and male to female ratio of 7/1 were examined for the presence of cutaneous manifestations of SLE. The most co...