نتایج جستجو برای: chronic pain scales gcps

تعداد نتایج: 809222  

بیجاری, بیتا, مصطفویان, سیده زهرا, نجومی, مرضیه, کاشانیان, مریم,

Background: symptoms of this with an overall negative impact on the psychosocial parameters in the patients,leading to a significant reduction of health-related quality of life. The aim of this study was toevaluate health-related quality of life in patients with endometriosis.Endometriosis is a estrogen- depended and chronic gynecological disease. TheMethodshospitals affiliated Tehran Universit...

Journal: :Science 2017
Changgeng Peng Lili Li Ming-Dong Zhang Carolina Bengtsson Gonzales Marc Parisien Inna Belfer Dmitry Usoskin Hind Abdo Alessandro Furlan Martin Häring Francois Lallemend Tibor Harkany Luda Diatchenko Tomas Hökfelt Jens Hjerling-Leffler Patrik Ernfors

Nociception is protective and prevents tissue damage but can also facilitate chronic pain. Whether a general principle governs these two types of pain is unknown. Here, we show that both basal mechanical and neuropathic pain are controlled by the microRNA-183 (miR-183) cluster in mice. This single cluster controls more than 80% of neuropathic pain-regulated genes and scales basal mechanical sen...

2016
Marasha de Jong Sara W. Lazar Kiran Hug Wolf E. Mehling Britta K. Hölzel Alexander T. Sack Frenk Peeters Heidi Ashih David Mischoulon Tim Gard

Body awareness has been proposed as one of the major mechanisms of mindfulness interventions, and it has been shown that chronic pain and depression are associated with decreased levels of body awareness. We investigated the effect of Mindfulness-Based Cognitive Therapy (MBCT) on body awareness in patients with chronic pain and comorbid active depression compared to treatment as usual (TAU; N =...

2011
Mauricio O. Magalhães Leonardo O. P. Costa Manuela L. Ferreira Luciana A. C. Machado

Background: There are no clinimetrically tested instruments for measuring attitudes and beliefs of health care providers with regards to chronic low back pain in Brazil. Objectives: To translate and cross-culturally adapt the Pain Attitudes and Beliefs Scale for Physiotherapists (PABS.PT) into Brazilian-Portuguese and to test the clinimetric properties of the Brazilian-Portuguese versions of th...

2014
Alessandro Clemenzi Alessandra Pompa Paolo Casillo Luca Pace Elio Troisi Sheila Catani Maria Grazia Grasso

BACKGROUND Chronic pain is common in persons with multiple sclerosis (MS), but the co-morbidity of fibromyalgia (FM) has yet to be investigated in MS. Objectives of the study were to evaluate, among the various types of chronic pain, the frequency of FM in MS and its impact on MS patients' health-related quality of life (HRQoL). MATERIAL AND METHODS 133 MS patients were investigated for the p...

2014
Jeeyun Lee Insuk Sohn In-Gu Do Kyoung-Mee Kim Se Hoon Park Joon Oh Park Young Suk Park Ho Yeong Lim Tae Sung Sohn Jae Moon Bae Min Gew Choi Do Hoon Lim Byung Hoon Min Joon Haeng Lee Poong Lyul Rhee Jae J. Kim Dong Il Choi Iain Beehuat Tan Kakoli Das Patrick Tan Sin Ho Jung Won Ki Kang Sung Kim

Despite the benefits from adjuvant chemotherapy or chemoradiotherapy, approximately one-third of stage II gastric cancer (GC) patients developed recurrences. The aim of this study was to develop and validate a prognostic algorithm for gastric cancer (GCPS) that can robustly identify high-risk group for recurrence among stage II patients. A multi-step gene expression profiling study was conducte...

Journal: :American journal of human genetics 2005
Jennifer J Johnston Isabelle Olivos-Glander Christina Killoran Emma Elson Joyce T Turner Kathryn F Peters Margaret H Abbott David J Aughton Arthur S Aylsworth Michael J Bamshad Carol Booth Cynthia J Curry Albert David Mary Beth Dinulos David B Flannery Michelle A Fox John M Graham Dorothy K Grange Alan E Guttmacher Mark C Hannibal Wolfram Henn Raoul C M Hennekam Lewis B Holmes H Eugene Hoyme Kathleen A Leppig Angela E Lin Patrick Macleod David K Manchester Carlo Marcelis Laura Mazzanti Emma McCann Marie T McDonald Nancy J Mendelsohn John B Moeschler Billur Moghaddam Giovanni Neri Ruth Newbury-Ecob Roberta A Pagon John A Phillips Laurie S Sadler Joan M Stoler David Tilstra Catherine M Walsh Vockley Elaine H Zackai Touran M Zadeh Louise Brueton Graeme Charles M Black Leslie G Biesecker

Mutations in the GLI3 zinc-finger transcription factor gene cause Greig cephalopolysyndactyly syndrome (GCPS) and Pallister-Hall syndrome (PHS), which are variable but distinct clinical entities. We hypothesized that GLI3 mutations that predict a truncated functional repressor protein cause PHS and that functional haploinsufficiency of GLI3 causes GCPS. To test these hypotheses, we screened pat...

Journal: :Molecular and cellular neurosciences 2008
Tokiharu Sato Takashi Torashima Kazushi Sugihara Hirokazu Hirai Masahide Asano Katsuji Yoshioka

Cerebellar granule cell precursors (GCPs) proliferate in the outer part of the external granular layer (EGL). They begin their differentiation by exiting the cell cycle and migrating into the inner part of the EGL. Here we report that JSAP1, a scaffold protein for JNK signaling pathways, is expressed predominantly in the post-mitotic GCPs of the inner EGL. JSAP1 knockdown or treatment with a JN...

Journal: :Pain 2002
Judith A Turner Mark P Jensen Catherine A Warms Diana D Cardenas

Little research has examined the role of patient cognitive and behavioral responses, including catastrophizing, in adjustment to chronic pain associated with spinal cord injury (SCI). The objective of this study was to examine the associations of catastrophizing and specific pain coping strategies with pain intensity, psychological distress, and pain-related disability among individuals with ch...

2011
Jeannette Saner Jan Kool Rob A de Bie Judith M Sieben Hannu Luomajoki

BACKGROUND Non-specific low back pain (NSLBP) in subacute and chronic stages can be treated effectively with exercise therapy. Research guidelines recommend evaluating different treatments in defined subgroups of patients with NSLBP. A subgroup of patients with movement control impairment (MCI) improved significantly on patient specific function and disability in a previous case series after mo...

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