Pulmonary Hypertension (PH) associated to chronic respiratory diseases is currently classified in the 3rd group, as a mild to moderate form of pre-capillary PH that progressively complicates the prognosis of associated pulmonary disease. In clinical practice, however, some unresolved issues in the respiratory PH should be considered: 1) the PH heterogeneity in some respiratory diseases, such as...

There are now many guidelines that provide direction for the diagnosis and management of asthma and chronic obstructive pulmonary disease (COPD). However, both diseases are still underdiagnosed (or misdiagnosed) and undertreated. There is considerable evidence that treatment with anti-inflammatory drugs reduces morbidity and mortality in asthma. The evidence is growing regarding their effect on...

Background Given that all human organs have vitamin D receptors, it is not surprising that vitamin D3 de ciency can also cause disease symptoms in the lungs. Known diseases include productive and obstructive bronchitis, asthma, chronic obstructive pulmonary disease (COPD), and frequent respiratory infections [1, 2]. To date, there is insu cient data to support whether vitamin D replacement impr...

The mounting burden of chronic respiratory diseases Chronic respiratory diseases (CRDs) are chronic diseases of the airways and other structures of the lungs. Major CRDs are asthma and respiratory allergies, chronic obstructive pulmonary disease (COPD), occupational lung diseases, sleep apnoea syndrome and pulmonary hypertension. Globally, they affect 1 billion people and account for 7% of all ...

Background: Chronic obstructive pulmonary disease (COPD) is a major burden and leading cause of death worldwide. Comorbidities such as gastroesophageal reflux, arrhythmia, musculoskeletal disorders cancer affect the quality life COPD patients. Psychological factors, perception, active coping with disease, anxiety depression may also daily activities life.

Nighttime symptoms are important indicators of impairment for many diseases and particularly respiratory such as chronic obstructive pulmonary disease (COPD). The use wearable sensors to assess sleep in COPD has mainly been limited the monitoring limb motions or duration continuity sleep. In this paper we present an approach concisely describe patterns subjects with without COPD. methodology co...

BACKGROUND Levels of Interleukin-6 (IL-6) and C-creative protein (CRP) indicating systemic inflammation are known to be elevated in chronic diseases including chronic obstructive pulmonary disease (COPD) and depression. Comorbid depression is common in patients with COPD, but no studies have investigated whether proinflammatory cytokines mediate the association between pulmonary function and de...

Vaccines play a major role in preventing potentially life-threatening diseases. More attention is now focused on the adult population, particularly as they age, as a reservoir for vaccine-preventable diseases. Adults with comorbid conditions such as asthma and chronic obstructive pulmonary disease (COPD) are considered to be at higher risk for invasive diseases, many of which are preventable th...

Although asthma has been viewed mainly as an eosinophilic disease, and chronic obstructive pulmonary disease (COPD) as a neutrophilic disease, recent studies have shown increased neutrophil counts in severe asthma and sputum eosinophilia in some COPD patients. In an attempt to further characterise these two syndromes according to pathology, the current authors have conducted a study of induced ...

Despite the different pathological features of COPD and asthma, two diseases often present similar clinical characteristics. In both diseases, patients suffer from exertional dyspnea other medical conditions. Pulmonary rehabilitation in has been reported to have various effects, including reduced dyspnea, improved quality life, increased aerobic capacity. Although there are few results on pulmo...