OBJECTIVE Obstructive lung disease is a major complication of bone marrow transplantation related to graft-versus-host disease. The purpose of this study was to determine the usefulness of high-resolution CT to evaluate obstructive lung disease occurring in children after bone marrow transplantation. MATERIALS AND METHODS Ten high-resolution CT scans of the lungs were obtained in seven childr...

8-Isoprostane is a potential in vivo marker for oxidant burden, but its usefulness in induced sputum of smokers and chronic obstructive pulmonary disease (COPD) has not been investigated. The current study investigated 58 subjects comprising 11 never-smokers, 11 ex-smokers, 13 healthy current smokers and 23 COPD with stage 0-III disease (according to the Global Initiative for Chronic Obstructiv...

objective: sulfur mustard (sm) is a potent mutagenic agent that targets several organs, particularly lung tissue. changes in morphological structure of the airway system are associated with chronic obstructive pulmonary deficiency following exposure to sm. although numerous studies have demonstrated pathological effects of sm on respiratory organs, unfortunately there is no effective treatment ...

the use of flow cytometry in the clinical laboratory has grown substantially in the past decade. flow cytometric analysis provides a rapid qualitative and quantitative description of multiple characteristics of individual cells. for example, it is possible to detect the cell size and granularity, aspects of dna and rna content and the presence of cell surface and nuclear markers which are used ...

Chronic obstructive pulmonary disease is characterized by the gradual progression of irreversible airflow obstruction and increased inflammation in the airways and lung parenchyma that is generally distinguishable from the inflammation caused by asthma. Most chronic obstructive pulmonary disease is associated with smoking, but occupational exposure to irritants and air pollution also are import...

Background: The vascular response to recurrent tissue hypoxia and reperfusion following red blood cell sickling causes acute chest syndrome and chronic lung disease. The purpose of this study was to determine the pattern of chronic lung lesions and possible risk factors in sickle cell patients in lagos, Nigeria.Methods: From July 2012 to April 2013, Pulmonary function test (PFT) and chest-x-ray...

Introduction Normal Physiology during Sleep: Changes with Maturation and Development Changes in Respiration during Sleep Thoracic Mechanics Upper Airway Ventilatory Control Arousal Apnea Gas Exchange Obstructive Sleep Apnea Syndrome Epidemiology Pathophysiology Complications Evaluation Treatment Long-term Outcome Central Hypoventilation Syndromes Definition Etiology Evaluation Treatment Chronic...

This letter arises from discussions and correspondence between colleagues involved in respiratory research or the diagnosis and treatment of lung diseases, as well as from a review of the literature on chronic obstructive pulmonary disease (COPD). As discussed below, it is written in the hope that we can persuade members of the Global Initiative for Chronic Obstructive Lung Disease (GOLD) commi...

Objective: Chronic obstructive pulmonary disease (COPD) is characterized by systemic inflammation and accelerated inflammaging of the lungs. Some studies showed that conjugated linoleic acid (CLA) has anti-inflammatory effects. The aim of the present study was to evaluate the effect of CLA supplementationon serum levels of interleukin (IL)-6 and sirtuin1 (SIRT1) in patients wit...