Previous transcriptional studies in heat-stressed corals have shown that many genes are responsive to generalized heat stress whereas the expression patterns of specific gene networks after heat stress show strong correlations with variation in bleaching outcomes. However, where these specific genes are expressed is unknown. In this study, we employed in situ hybridization to identify patterns ...

Brivanlou and Melton, 1992; Kessler and Melton, 1994; Schulte-Merker et al., 1994). At a later stage, signals Clare Hudson, Debbie Clements, Rosalind V. Friday, David Stott, and Hugh R. Woodland* originating in the dorsal organizer region (e.g., noggin, Department of Biological Sciences chordin, and nodal-related molecules) and local signalUniversity of Warwick ing molecules in the ventral and ...

Dorsoventral patterning in animal development is regulated by a morphogenetic gradient of Bone morphogenetic protein signalling, which is established by a set of proteins that are conserved from Drosophila to vertebrates. These include Chordin (Chd)/Short gastrulation, Xolloid/Tolloid and Twisted gastrulation. Here, we report the identification of a cell-surface component of this morphogenetic ...

We performed in vivo experiments in chick embryos that examined whether application of an exogenous source of Shh protein mimics the ability of the notochord to induce ectopic floor plate cells in the neural tube. Shh cannot act alone to induce a floor plate. However, coapplication of Shh and chordin, a BMP antagonist normally coexpressed with Shh in the notochord, results in a marked switch fr...

A growing body of work indicates that neural induction may be initiated prior to the establishment of the gastrula mesodermal organizer. Here, we examine neural induction in Xenopus embryos in which mesoderm induction has been blocked by Cerberus-short, a reagent that specifically inhibits Nodal-related (Xnr) signals. We find that extensive neural structures with cyclopic eyes and brain tissue ...

We have investigated the molecular interactions underlying neural crest formation in Xenopus. Using chordin overexpression to antagonize endogenous BMP signaling in whole embryos and explants, we demonstrate that such inhibition alone is insufficient to account for neural crest induction in vivo. We find, however, that chordin-induced neural plate tissue can be induced to adopt neural crest fat...

Dorsoventral pattering relies on Toll and BMP signalling in all insects studied so far, with variations the relative contributions of both pathways. Drosophila beetle Tribolium share extensive dependence Toll, while representatives more distantly related lineages like wasp Nasonia bug Oncopeltus rely strongly signalling. Here, we show that cricket Gryllus bimaculatus , an evolutionarily distant...