Mutations in the C1 inhibitor gene that result in low functional levels of C1 inhibitor protein cause hereditary angioneurotic edema. This disease is characterized by episodic edema leading to considerable morbidity and death. Among 60 unreported kindred with the disease, four patients were discovered to have mutations clustered within a 12-bp segment of exon 5 from nucleotide 8449 to nucleotid...

AFT fan noise radiating from the bypass exhaust duct is usually attenuated by acoustic lining along the inside of the duct only. The unconventional treatment of the afterbody, recently proposed by Tester et al. [1–3] has been shown to provide an additional potential of damping of the order of 1 to 4 dB. This is remarkable, given the fact that most of the sound is supposed to radiate away from, ...

The Echinococcus granulosus genome was searched for microsatellites using 8 different repeated oligonucleotides as probes (GT15, CT15, AT15, CG15, CAT10, CAA10, CGG10 and CATA10). Southern blot experiments revealed that DNA regions containing GT, CAA, CATA and CT repeats are the most frequent in the E. granulosus genome. AT and CG probes showed no hybridization signal. Two loci containing CA/GT...

The exocyclic 1, N(2)-ethenodeoxyguanosine (1,N(2)-is an element of dG) adduct, arising from the reaction of vinyl halides and other vinyl monomers, including chloroacetaldehyde, and lipid peroxidation products with dG, was examined at pH 5.2 in the oligodeoxynucleotide duplex 5'-d(CGCATXGAATCC)-3'.5'-d(GGATTCCATGCG)-3' (X = 1,N(2)-is an element of dG). Previously, X(anti).C(anti) pairing was e...

Introduction Over the last few years, a new generation of satellite sensors has provided an unprecedented variety of remotely sensed imagery with a spatial resolution of 1 m and better. These images allow for the first time even small archaeological sites and features to be detected, which is a huge step forward for archaeological prospection: “For three decades archaeologists have waited for a...

Relevant Panacea Deliverables D3.1 Architecture and Design of the Platform (T6) D4.1 Technologies and tools for corpus creation, normalization and annotation (T6) D4.2 Initial functional prototype and documentation describing the initial CAA subsystem and its components (T13) D4.3 Monolingual corpus acquired in five languages and two domains (T14) D5.1 Parallel technologies tools for PANACEA (T...

To determine the long-term cost-benefit of intravenous immunoglobulin (IVIG) treatment in Children with Kawasaki Disease (KD), a model was made to compare the total cost for management of these children with and without the use of IVIG. Long-term (10-21 years) follow-up of 594 KD patients treated in the pre-IVIG era reported by Kato, et al. was used to calculate cost using previous cost studies...

The nucleotide sequence of T4 species I RNA, one of several stable RNA's specifically coded for by bacteriophage T4, has been determined using 32-P-labeled material from T4-infected cultures of Escherichia coli. The purified RNA species which has been sequenced has been shown to hybridize well to T4 DNA (Wilson J.H., Kim, J.S., and Abelson, J.N. (1972) J. Mol. Biol. 71, 547-556). The sequence i...

In order to discern sake yeast, shochu yeast, and wine yeast, a specific polymerase chain reaction (PCR) was investigated. PCR products between shochu yeast strains and sake yeast weredistinguished by using a primer designed with an open reading frame of FLO5. Wine yeasts and most of other yeasts were distinguished by a primer designed with an open reading frame of YHR213W.However, PCR products...

We review accumulating evidence that cerebrovascular amyloid deposition (cerebral amyloid angiopathy [CAA]) is an independent risk factor for cognitive dysfunction. The two population-based autopsy studies that have analyzed cognitive status during life as a function of CAA have each suggested deleterious effects of CAA on cognition even after controlling for age and Alzheimer disease pathology...