Abstract The Apoptosis is an intensely studied mechanism for cancer therapy. Various genes, drugs, and molecules have been combined to potentiate the apoptotic effect against tumor cells. Magnetic nanocomplexes with biopolymers proposed as nanocarriers delivery of active improve apoptosis induction. To these purpose were formulated magnetic nanoparticles curcumin coated chitosan (MNPs-CHI-TPP-C...

Development of oral amphotericin B (AmB) loaded nanoparticles (NPs) demands a novel technique which reduces its toxicity and other associated problems. Packing of AmB in between two oppositely charged ions by polyelectrolyte complexation technique proved to be a successful strategy. We have developed a novel carrier system in form of polyelectrolyte complex of AmB by using chitosan (CS) and por...

Bioactive composites that enable the formation of calcium phosphates have received increased attention over the last decade, in the development of osteoconductive biomaterials for orthopaedic applications. In this work, tripolyphosphate (TPP)-cross-linked chitosan/gelatin composites (TPP-CG) were prepared for the growth of shape- and size-controlled calcium phosphates on/in the composites. The ...

Polycyclic aromatic hydrocarbons (PAHs) pose risks to human and animal health, their accumulation in crops is a concern for the food chain environment. Nanoparticles (NPs) have shown potential chemical delivery can be used enhance plant resistance PAHs. In this study, carotenoid-coated chitosan nanoparticles (CCNPs) loaded with β-carotene were prepared applied spinach grown PAH-contaminated soi...

Aim Nucleotide analogues such as Azidothymidine-triphosphate (AZT-TP), the active form of Zidovudine, display an important pharmacological activity for the treatment of HIV. The administration of these nucleotide analogues would bypass the intracellular phosphorylation which can be a metabolic bottleneck. This possibility is however limited by their instability in physiological conditions, and ...

Objective(s): Nanoparticles (NPs) are known for their specific accumulation in the inflamed tissues of the colon and thus allow a selective delivery to the site of inflammation with minimum adverse effects. The main objective of this work is to attain mesalamine loaded chitosan nanoparticles as a carrier for oral delivery. Methods: In this study, me...

meso-Tetraphenylporphyrin (TPP) and its two substituted derivatives (meso-tetrakis(4-cyanophenyl)porphyrin [TPP(CN)4] and meso-tetrakis(4-methoxyphenyl)porphyrin [TPP(OMe)4]) were synthesized. Their nonlinear absorption and refraction properties were studied using the Z-scan technique in the picosecond (ps) and nanosecond (ns) regimes. The open aperture Z-scan results reveal that TPP and TPP(CN...

Bromeliads are used in landscaping due to the beauty of their leaves and flowers. The use plant regulators such as nitric oxide (NO) promotes stimulus germination it has been a way out enhance production reduce search for plants nature nanoencapsulation aims optimize its effect. objective this work was evaluate effect using free nanoencapsulated NO donor on D. excelsa. treatments consisted soak...

Using low molecular weight chitosan nanoparticles (CNPs) prepared by an ionic gelation method, we report the effect of low-intensity pulsed ultrasound (US) on cell viability and nanoparticle uptake in cultured murine pre-osteoblasts. Particle size and zeta potential are measured using Dynamic Light Scattering (DLS), and cell viability is evaluated using the MTS assay. Results show that 30 min d...

Thiamine pyrophosphate (TPP), a biologically active form of thiamine (vitamin B₁), is an essential cofactor in all living systems. Microorganisms either synthesize TPP via de novo biosynthesis pathways or uptake exogenous thiamine from the environment via specific transporters. The oral spirochete Treponema denticola is an important pathogen that is associated with human periodontal diseases. I...