نتایج جستجو برای: chitosan microspheres

تعداد نتایج: 28232  

A Rezaei Mokarram SA Mortazavi

Preparation of chitosan (CS) microspheres as a novel drug delivery vehicle for intranasal immunization using high, medium and low CS molecular weight (MW) was investigated in this study. Diphtheria toxoid (DT) was used as a model antigen. The emulsion-solidification method was adopted for microencapsulation of DT.  In the first step, following the purification of semi-crude DT by the ion-exchan...

Journal: :Journal of visualized experiments : JoVE 2012
David O Zamora Shanmugasundaram Natesan Robert J Christy

Multipotent stem cells have been shown to be extremely useful in the field of regenerative medicine. However, in order to use these cells effectively for tissue regeneration, a number of variables must be taken into account. These variables include: the total volume and surface area of the implantation site, the mechanical properties of the tissue and the tissue microenvironment, which includes...

2016
Lu Shan En-Xue Tao Qing-Hui Meng Wen-Xia Hou Kang Liu Hong-Cai Shang Jin-Bao Tang Wei-Fen Zhang

Cholinergic neurotransmission loss is the main cause of cognitive impairment in patients with Alzheimer's disease. Phospholipids (PLs) play an essential role in memory and learning abilities. Moreover, PLs act as a source of choline in acetylcholine synthesis. This study aimed to prepare and optimize the formulation of chitosan/phospholipid/β-cyclodextrin (CTS/PL/β-CD) microspheres that can imp...

Journal: :International Journal of Drug Delivery 2011

Journal: :Journal of Biomaterials and Nanobiotechnology 2011

Journal: :Journal of Applied Pharmaceutical Science 2015

2011

Polymeric beads with diameter in the micrometer range find use in vanous medical applications, such as bone cements', in local delivery of drugs' and in treatment of female stress urinary incontinence.r" Medical microspheres usually consists of poly (methyl methacrylate), poly (lactic acid-eo-glycolic acid), poly (tetra fluoroethylene) or silicone rubbers. A particularly important application o...

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