نتایج جستجو برای: chemotaxis

تعداد نتایج: 11698  

Journal: :Thorax 1984
E Lemarie P Carre M F Legrand M Lavandier E Boissinot M Renoux G Renoux

Alveolar macrophage chemotaxis was measured in 129 individuals--13 normal volunteers, 15 tumour free patients with recent bronchopulmonary infections, 10 patients with chronic bronchitis, 29 patients with endothoracic sarcoidosis, 48 patients with primary bronchial carcinoma and 14 patients with pulmonary metastases from various origins. Chemotaxis was tested in the presence of either zymosan a...

Journal: :Arteriosclerosis and thrombosis : a journal of vascular biology 1991
E B Schmidt J O Pedersen K Varming E Ernst C Jersild N Grunnet J Dyerberg

Dietary supplementation with n-3 polyunsaturated fatty acids (n-3 PUFAs) has been shown to inhibit neutrophil and monocyte chemotaxis in healthy subjects and, with respect to neutrophils, also in various patient groups. We studied the effect of dietary supplementation with n-3 PUFAs on monocyte and neutrophil chemotaxis in patients with hyperlipidemia. Chemotaxis was investigated with the under...

Journal: :American journal of respiratory cell and molecular biology 2008
Mitsu Hashimoto Xingqi Wang Lijun Mao Tetsu Kobayashi Shin Kawasaki Naoyoshi Mori Myron L Toews Hui Jung Kim D Roselyn Cerutis Xiangde Liu Stephen I Rennard

Migration of fibroblasts plays an essential role in tissue repair after injury. Sphingosine 1-phosphate (S1P) is a multifunctional mediator released by many cells that can be released in inflammation and after injury. This study evaluated the effect of S1P on fibroblast chemotaxis toward fibronectin. S1P alone did not affect fibroblast migration, but S1P enhanced fibronectin-directed chemotaxis...

Journal: :Neuron 2014
Linjiao Luo Quan Wen Jing Ren Michael Hendricks Marc Gershow Yuqi Qin Joel Greenwood Edward R. Soucy Mason Klein Heidi K. Smith-Parker Ana C. Calvo Daniel A. Colón-Ramos Aravinthan D.T. Samuel Yun Zhang

Brain circuits endow behavioral flexibility. Here, we study circuits encoding flexible chemotaxis in C. elegans, where the animal navigates up or down NaCl gradients (positive or negative chemotaxis) to reach the salt concentration of previous growth (the set point). The ASER sensory neuron mediates positive and negative chemotaxis by regulating the frequency and direction of reorientation move...

2015
Xuehua Xu Nidhi Gera Hongyan Li Michelle Yun Liyong Zhang Youhong Wang Q. Jane Wang Tian Jin

Chemotaxis requires precisely coordinated polymerization and depolymerization of the actin cytoskeleton at leading fronts of migrating cells. However, GPCR activation-controlled F-actin depolymerization remains largely elusive. Here, we reveal a novel signaling pathway, including Gαi, PLC, PKCβ, protein kinase D (PKD), and SSH2, in control of cofilin phosphorylation and actin cytoskeletal reorg...

2014
Alexandra Ruth Petlick Pascale G. Charest

Chemotaxis is a process whereby singleand multi-cellular organisms migrate in response to external chemical stimuli. This directed cell movement is regulated by complex signaling pathways and is implicated in embryonic development, immune response, and the metastasis of cancer cells. Dictyostelium discoideum, social amoebae with the ability to migrate and aggregate in response to chemoattractan...

Journal: :Computation (Basel) 2021

Chemotaxis describes the movement of an organism, such as single or multi-cellular organisms and bacteria, in response to a chemical stimulus. Two widely used models describe phenomenon are celebrated Keller–Segel equation chemotaxis kinetic equation. These two equations organism’s at macro- mesoscopic level, respectively, asymptotically equivalent parabolic regime. The way which organism respo...

Journal: :The Journal of Experimental Medicine 1968
Peter A. Ward Elmer L. Becker

As shown previously, immune complexes engender in rabbit serum a factor capable of inducing chemotaxis of rabbit polymorphonuclear leukocytes. This chemotactic factor consists of a complex of the fifth, sixth, and seventh components of complement. As demonstrated here, the polymorphonuclear leukocytes incubated with such treated rabbit serum lose their ability to respond chemotactically to the ...

2014
Elena Ermilova Zhanneta Zalutskaya

Nitrite plays an important role in the nitrogen metabolism of most cells, including Chlamydomonas reinhardtii. We have shown that vegetative cells of C. reinhardtii are attracted by nitrite. The Nia1nit2 mutant with defects in genes encoding the nitrate reductase and regulatory protein NIT2 respectively was found to exhibit normal chemotaxis to nitrite. The data suggest that chemotaxis events a...

Journal: :The Journal of Cell Biology 1989
P R Fisher R Merkl G Gerisch

An image processing system was programmed to automatically track and digitize the movement of amebae under phase-contrast microscopy. The amebae moved in a novel chemotaxis chamber designed to provide stable linear attractant gradients in a thin agarose gel. The gradients were established by pumping attractant and buffer solutions through semipermeable hollow fibers embedded in the agarose gel....

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