Safety thresholds for chemical impurities and leachables in consumer products such as foods and drugs have helped to ensure public health while establishing scientifically sound limits for identification and risk assessment of these compounds. The Product Quality Research Institute (PQRI) Leachables and Extractables Working Group, a collaboration of chemists and toxicologists from the U.S. Food...

This paper identifies the software information that must be represented in a formal specification of source code level “safety verification conditions” (SVCs) for an object-oriented software system. The formalization does not necessarily require a notation with object-oriented constructs. In particular, a semantically simpler notation based on typed predicate logic is adequate for representing ...

This paper introduces a novel modeling and statistical framework (based on Bayesian theory) that utilizes extensive distributed control system and emergency shutdown databases, to perform thorough risk and vulnerability assessment of chemical/petrochemical plants. Quality variables are utilized, in addition to safety (or process) variables, to enhance both process safety and product quality. To...

8 Increasing oil temperature and heating duration in deep-fat frying of potato chips can improve textural quality but worsen the chemical safety of acrylamide formation. Optimal design of this complex process is formulated as a non-linear constrained optimization problem where the objective is to compute the oil temperature profile that guarantees the desired final moisture content while minimi...

for the Mary Kay O’Connor Process Safety Center 2013 International Symposium, October 22-24, 2013, College Station, Texas. Overcoming PSM Challenges for Small Sites and Chemical Companies: Observations, Insights, and Guidance from the Trenches Philip M. Myers Advantage Risk Solutions, Inc. PO Box 510 Sunbury, OH 43074 Ph (740) 965-6304 [email protected]

The paper focuses on the issues of health and safety management in chemical industry enterprises. First, the significance of health and safety management for chemical industry enterprises is presented, followed by approaches to this area, including the selected results that have been achieved since 1998 within European chemical industry. Attention is primarily paid to the occupational health pr...

The Polish version of/International Chemical Safety Cards is based on the translation of the International Chemical Safety Card (ICSC) developed within the International Programme on Chemical Safety (IPCS) in cooperation with and financial support of the Commission of the European Communities (CEC). International Chemical Safety Cards comprise basic information and requirements in the field of ...