From accumulating studies of hexameric helicases, a mechano-chemical coupling mechanism has emerged which postulates that the nucleoside triphosphate (NTP) hydrolysis is sequentially coordinated together with the binding and translocation of nucleic acid substrate. Various mechano-chemical models have been proposed for different hexameric helicases with no consensus for a common mechanism. To e...

An adaptive model reduction algorithm is proposed for systems of ODEs from chemical kinetics. Its goal is to provide an accurate approximation to the solution of these systems faster than could be obtained through straightforward numerical integration. The algorithm approximates a system with a sequence of reduced models, each one appropriate to the dynamics of the system during a period of the...

Gamma is a programming model where computation is seen as chemical reactions between data represented as molecules floating in a chemical solution. Formally, this model is represented by the rewriting of a multiset where rewrite rules model the chemical reactions. Recently, we have proposed the γ-calculus, a higher-order extension, where the rewrite rules are first-class citizen. The work prese...

Remote detection and identification of chemicals in a scene is a challenging problem. We introduce an approach that uses some of the image’s pixels to establish the background characteristics while other pixels represent the target for which we seek to identify all chemical species present. This leads to a generalized least squares problem in which we focus on “subset selection” to identify the...

Introduction Conclusions References Tables Figures Back Close Full Screen / Esc Biogeosciences Discussions This discussion paper is/has been under review for the journal Biogeosciences (BG). Please refer to the corresponding final paper in BG if available. Abstract Introduction Conclusions References Tables Figures Back Close Full Screen / Esc Abstract Chemical transport models (CTMs), used for...

Learning is the nature for human being. For example, a school-student learns a subject by doing exercise and home-work. Then, a school-teacher grades the school-student’s works. From this student and teacher interaction, the ability of the student mastering the subject is a feedback that the previous teaching method is successful or failure. As a result, the teacher will change the teaching met...

MOTIVATION The increasing number and complexity of biomodels makes automatic procedures for checking the models' properties and quality necessary. Approaches like elementary mode analysis, flux balance analysis, deficiency analysis and chemical organization theory (OT) require only the stoichiometric structure of the reaction network for derivation of valuable information. In formalisms like Sy...

CONTEXT The main objectives of triage are securing patient safety during the process of emergency diagnosis and treatment, and reduction of waiting time for medical services and transport. To date, there is no triage system for nerve agent victims. EVIDENCE ACQUISITION This systematic review proposes a new triage system for patients exposed to nerve agents. Information regarding clinical sign...

A simple model is proposed that describes the various morphodynamic principles of migrating cells from polar to amoeboidal motions. The model equation is derived using competing internal cellular compass variables and symmetries of the system. Fixed points for the N = 2 system are closely investigated to clarify how the competition among polaritors explains the observed morphodynamics. Response...