نتایج جستجو برای: chd

تعداد نتایج: 8315  

2012
Benjamin Shillinglaw Anthony J Viera Teresa Edwards Ross Simpson Stacey L Sheridan

BACKGROUND Global coronary heart disease (CHD) risk assessment is recommended to guide primary preventive pharmacotherapy. However, little is known about physicians' understanding and use of global CHD risk assessment. Our objective was to examine US physicians' awareness, use, and attitudes regarding global CHD risk assessment in clinical practice, and how these vary by provider specialty. M...

Journal: :Genome research 2013
M Reza Sailani Periklis Makrythanasis Armand Valsesia Federico A Santoni Samuel Deutsch Konstantin Popadin Christelle Borel Eugenia Migliavacca Andrew J Sharp Genevieve Duriaux Sail Emilie Falconnet Kelly Rabionet Clara Serra-Juhé Stefano Vicari Daniela Laux Yann Grattau Guy Dembour Andre Megarbane Renaud Touraine Samantha Stora Sofia Kitsiou Helena Fryssira Chariklia Chatzisevastou-Loukidou Emmanouel Kanavakis Giuseppe Merla Damien Bonnet Luis A Pérez-Jurado Xavier Estivill Jean M Delabar Stylianos E Antonarakis

Congenital heart defect (CHD) occurs in 40% of Down syndrome (DS) cases. While carrying three copies of chromosome 21 increases the risk for CHD, trisomy 21 itself is not sufficient to cause CHD. Thus, additional genetic variation and/or environmental factors could contribute to the CHD risk. Here we report genomic variations that in concert with trisomy 21, determine the risk for CHD in DS. Th...

Journal: :BMC Public Health 2007
Zubair Kabir Kathleen Bennett Emer Shelley Belgin Unal Julia A Critchley Simon Capewell

BACKGROUND To investigate whether primary prevention might be more favourable than secondary prevention (risk factor reduction in patients with coronary heart disease(CHD)). METHODS The cell-based IMPACT CHD mortality model was used to integrate data for Ireland describing CHD patient numbers, uptake of specific treatments, trends in major cardiovascular risk factors, and the mortality benefi...

Background: Extracardiac malformations can be seen in 20-45% of infants with congenital heart disease (CHD). Chromosomal abnormalities exist in 5-10% of patients with CHD. The aim of this study was to assess the frequency of overt extra cardiac malformations in children with CHD. Methods: This descriptive epidemiologic study was conducted on 720 patients with CHD referred to the pediatric ca...

Journal: Health Science Monitor 2022
Ali Zolfi, Erfan Farhadi, Mohammad Radvar, Zahra Fakour,

Background & Aims:  Congenital heart disease (CHD) is the most common congenital anomaly, accounting for 28% of all congenital anomalies in infants. The present study was performed to determine the frequency, demographic characteristics, and clinical outcomes in neonates with CHD. Materials & Methods: This cross-sectional, descriptive-analytical study was conducted on 341 neonates with CHD adm...

Journal: :International journal of epidemiology 2015
Xiaocheng Liu Gongshu Liu Ping Wang Yunzhou Huang Enqing Liu Dongbei Li Shutang Ren Lei Pan Nan Li Xilin Yang Zhijie Yu Gang Hu

BACKGROUND Congenital heart disease (CHD) represents one of the most prevalent congenital malformations. However, few studies use whole-population screening by colour Doppler ultrasonic diagnostic system to identify CHD among live infants. We estimate the prevalence of CHD and its major risk indicators among infants aged less than 6 months in urban Tianjin, China. METHODS A colour Doppler ult...

Journal: :International journal of clinical and experimental pathology 2015
Xiao-Fei Li Chun-Hui Song Hong-Zhuan Sheng Dong-Dong Zhen Min Pan Jian-Hua Zhu

OBJECTIVE To investigate the relationship between P-selectin gene polymorphism and congenital heart disease (CHD) with pulmonary hypertension (PAH). METHODS 58 CHD patients with PAH (PAH-CHD), 43 CHD patients without PAH and 205 healthy subjects were included in this study. The concentration of plasma P-selectin was determined by ELISA kits; the direct sequencing of PCR products was used to a...

Journal: :BMC Family Practice 2007
Barbara P Yawn Peter C Wollan Roy A Yawn Steven J Jacobsen Veronique Roger

BACKGROUND CHD is a chronic disease often present years prior to incident AMI. Earlier recognition of CHD may be associated with higher levels of recognition and treatment of CHD risk factors that may delay incident AMI. To assess timing of CHD and CHD risk factor diagnoses prior to incident AMI. METHODS This is a 10-year population based medical record review study that included all medical ...

Journal: :American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2014
James J Yi Sunny X Tang Donna M McDonald-McGinn Monica E Calkins Daneen A Whinna Margaret C Souders Elaine H Zackai Elizabeth Goldmuntz James W Gaynor Ruben C Gur Beverly S Emanuel Raquel E Gur

Children with 22q11.2 deletion syndrome (22q11DS) present with congenital heart disease (CHD) and high prevalence of psychiatric disorders and neurocognitive deficits. Although CHD has been implicated in neurodevelopment, its role in the neuropsychiatric outcome in 22q11DS is poorly understood. We investigated whether CHD contributes to the high prevalence of psychiatric disorders and neurocogn...

2017
Mengqi Huo Zhixin Wang Dongxue Wu Yanling Zhang Yanjiang Qiao

Salvia miltiorrhiza, known as Danshen, has attracted worldwide interest for its substantial effects on coronary heart disease (CHD). Danshensu (DSS) is one of the main active ingredients of Danshen on CHD. Although it has been proven to have a good clinical effect on CHD, the action mechanisms remain elusive. In the current study, a coexpression network-based approach was used to illustrate the...

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