The Chemical Hamiltonian Approach ~CHA! versions of the Roothaan and Kohn–Sham equations, labeled CHA/F and CHA/DFT, respectively, have been used to obtain the basis set superposition error ~BSSE!-corrected first-order electron density of the hydrogen fluoride dimer with several basis sets. We have analyzed the effect of BSSE in terms of the electronic relaxation, i.e., the redistribution of th...

Due to osteoconductivity of hydroxyapatite (HA), HA/polymer composite scaffolds have been investigated for bone tissue engineering by various groups. In scaffold fabrication, electrospinning of ultrafine fibrous scaffolds incorporated with substantial amounts of evenly distributed HA nanoparticles is still a challenge. The problem of nanoparticle agglomeration not only reduces the electrospinni...

Jack Goldstone argues that Comparative Historical Analysis (CHA) holds a distinct epistemological orientation vis-a-vis large-N , frequentist approaches that has proven to be particularly fertile for the study of revolutions. He begins by sketching this CHA epistemology, focusing on its use of Bayesian analysis, process tracing, and congruence testing. Goldstone then proceeds to show, via a his...

background Chronic heavy alcohol (CHA) use has been associated with perioperative complications. Emergency general surgery (EGS) patients are not routinely screened for CHA. If screened, it is usually for hazardous use of alcohol, using a survey such as the Alcohol Use Disorders Identification Test (AUDIT). This study screened EGS patients for CHA use using serum carbohydrate-deficient transfer...

We examined the effects of a chloroform extract of Hyptis albida (CHA) on inflammatory responses in mouse lipopolysaccharide (LPS) induced peritoneal macrophages. Our findings indicate that CHA inhibits LPS-induced production of tumor necrosis factor (TNF- α ) and interleukin-6 (IL-6). During the process, levels of cyclooxygenase-2 (COX-2), nitric oxide synthase (iNOS), and nitric oxide (NO) in...

OBJECTIVE To study the influence of a possible interaction between maternal smoking and high body mass index (BMI) on the occurrence of specific congenital heart anomalies (CHA) in offspring. DESIGN Case-control study. SETTING Data from a population-based birth defects registry in the Netherlands. PATIENTS Cases were 797 children and fetuses born between 1997 and 2008 with isolated non-sy...

Carbonate-substituted hydroxyapatite (CHA) is more osteoconductive and more resorbable than hydroxyapatite (HA), but the underlying mode of its action is unclear. We hypothesised that increased resorption of the ceramic by osteoclasts might subsequently upregulate osteoblasts by a coupling mechanism, and sought to test this in a large animal model. Defects were created in both the lateral femor...

The mechanism of relaxation in the rat tail artery induced by the adenosine A(1) receptor-selective agonist N(6)-cyclohexyladenosine (CHA, 10 nM-300 microM) and the adenosine A1/A(2a) receptor agonist 5'-N-ethylcarboxamidoadenosine (NECA, 10 nM-300 microM) has been characterized. To do this, we used alpha(1)-receptor agonist phenylephrine to evoke contraction (10 microM), and inhibitors of nitr...

Low-molecular-weight polyethylenimine has lower cytotoxicity than high molecular weight polyethylenimine, but it is not an efficient transfection agent because of limitations of DNA delivery into the cytoplasm. Therefore, in the present study, the hydrophobic modification of low-molecular-weight polyethylenimine (PEI 2 kDa [PEI2]) by cholic acid (ChA) was performed to form PEI2-ChA, and in vitr...