Because of the relatively frequent occurrence of recurrent caries after a restorative treatment, and because of the huge number of cariogenic microorganisms present in the oral cavity, which present a potential risk factor regarding the development of new carious lesions, attention has increasingly been directed towards the therapeutic antimicrobial effects of restorative materials. The glass i...

Chorda tympani taste nerve responses to NaCl can be dissected pharmacologically into amiloride-sensitive and -insensitive components. It is now established that the amiloride-sensitive, epithelial sodium channel acts as a sodium-specific ion detector in taste receptor cells (TRCs). Much less is known regarding the cellular origin of the amiloride-insensitive component, but its anion dependence ...

11 Abstract Various kinds of multiple organ failure (MOF) are briefly compared. We argue that many MOF’s result from those esophageal perforations due to oral Candida. We focus on a “silent” MOF associated with gastric hypochlorhydria and describe a prophylactic regimen that: (1) greatly reduces oral Candida and is predicted to stop their esophageal perforations; and (2) prevents Candidal colon...

PURPOSE Bioadhesive polymers play an important role in biomedical and drug delivery applications. The aim of this study is to develop a sustained- release tablet for local application of Cetylpyridinium Chloride (CPC). This delivery system would supply the drug at an effective level for a long period of time, and thereby overcome the problem of the short retention time of CPC and could be used ...

Fluorescence techniques have been widely used for the determination of micellar aggregation numbers.' However, the interpretation of the fluorescence data and the consequent estimates for the micellar aggregation numbers are not always unambiguous. The results usually depend on both the type of experiments performed and the micellar models invoked for the data analysis. In an interesting recent...