first described by Gusserow in 1870 as a well differentiated adenocarcinoma in which most of the glands are impossible to be distinguished from the normal endocervical mucosa, although the MDA invades deep into the cervical stroma. At first, MDA was restricted to the mucinous type, but the definition of MDA has been expanded to other cell types, including the endometrioid, clear cell and nonspe...

Hemangioma is a benign tumor of blood and lymphatic vessels. It is common in skin, mucosa and soft tissues, and its occurrence in lymph nodes is extremely rare. A 10 year-old she-camel was slaughtered at Nyala slaughterhouse, South Darfur State, Sudan. Grossly, the carcass was emaciated. The left ventral superficial cervical lymph node was enlarged, hard on palpation and protruded outside the b...

Benign teratoma is the most common germ cell tumour found in ovary. One to three percent of these are harbour somatic neoplasms,1 which squamous carcinoma, adenocarcinoma and sarcoma account for 95%.2 The first report a carcinoid presenting bronchial mucosa, within was made 20183 we present similar rare case 54 year old female. patient underwent total laparoscopic hysterectomy bilateral salping...

we evaluated the specific pattern of pre- and postoperative neurological signs and symptoms of cervical spondylotic myelopathy (csm) to determine [mdings which had a predictive value for surgical outcome. consecutive patients with csm caused by osteophytic ridge or intervertebral disc herniation who underwent anterior cervical decompression and fusion in loghman hakim hospital from 1999-2003 we...

Cervical carcinoma infrequently involves the uterine corpus or adnexa. Metastatic adenocarcinoma (AC) to the ovaries can be difficult to distinguish from primary ovarian tumors, and metastatic squamous cell carcinoma (SCC) to these sites has not been well described. Our aim was to provide a detailed description of the morphologic patterns of adnexal and corpus involvement by cervical carcinoma....

BACKGROUND Identification of factors associated with the presence of human immunodeficiency virus (HIV) in female genital secretions is critical for intervention strategies targeting transmission and eliminating replication of genital virus. We sought to monitor the prevalence of genital HIV shedding in antiretroviral therapy-adherent women over time and to assess changes in the genital microen...

Focal adhesion kinase (FAK), a nonreceptor protein tyrosine kinase and key modulator of integrin signaling, is widely expressed in different tissues and cell types. Recent evidence indicates a central function of FAK in neoplasia where the kinase contributes to cell proliferation, resistance to apoptosis and anoikis, invasiveness, and metastasis. FAK, like other signaling kinases, is dependent ...

Although T lymphocytes are present in the genital mucosa, their function in sexually transmitted diseases is unproven. To determine if cervical T cells mediate HIV-specific cytolysis, mononuclear cells in cytobrush specimens from HIV-1-infected women were stimulated in vitro with antigen. Resultant cell lines lysed autologous targets expressing HIV-1 proteins in 12/19 (63%) subjects, and these ...

The human papillomavirus (HPV) family comprises more than 170 different types that preferentially infect the mucosa of the genitals, upper-respiratory tract, or the skin. The 'high-risk HPV type', a sub-group of mucosal HPVs, is the cause of approximately 5% of all human cancers, which corresponds to one-third of all virus-induced tumours. Within the high-risk group, HPV16 is the most oncogenic...

INTRODUCTION Breast lymphoma accounts for less than 1% of all non-Hodgkin's lymphomas and approximately 0.1% of all breast neoplasms. Most breast lymphomas are classified as diffuse large B-cell lymphomas or as mucosa associated lymphoid tissue lymphomas. Concurrent cases of breast lymphoma and cervical cancer are extremely rare. CASE PRESENTATION We report a case of a 46-year-old woman of un...