OBJECTIVE In early cervical cancer, a total pelvic lymphadenectomy is the standard of care, even though most patients have negative nodes and thus undergo lymphadenectomy unnecessarily. Although the value of sentinel lymph node (SLN) mapping in early-stage cervical cancer has not yet been established, near-infrared (NIR) fluorescence imaging is a promising technique to perform this procedure. N...

AIMS The purpose of this prospective study was to describe the incidence and distribution pattern of human papillomavirus (HPV) DNA in intraoperative dissected lymph nodes and to relate this to the pathological confirmation of metastasis. METHODS Samples of primary cervical cancer lesions and dissected lymph nodes were obtained from women undergoing surgical treatment. The presence of HPV DNA...

OBJECTIVE Kikuchi's disease (KD), or histiocytic necrotizing lymphadenitis, is a unique form of self-limiting lymphadenitis and typically affects the head and neck regions. It usually occurs in young adults and has a female predilection. The aim of this study was to review the authors' institutional experience with KD in children over a 16-year period. METHODS Between January 1986 and May 200...

BACKGROUND Oropharyngeal squamous cell carcinomas (OSCCs) are associated with high-grade human papillomavirus (HPV) infection in 20% to 30% of cases. HPV-16 DNA has been detected in cervical lymph node metastases of HPV-16(+) OSCC. However, the meaning of HPV-16 DNA detection in lymph nodes remains controversial. Does the presence of HPV-16 DNA in lymph nodes correlate with their metastatic inv...

breast cancer is one of the most common malignancies in the world. the most important prognostic factor in this cancer is the stage of the tumor. detection of lymph nodes with or without malignancy is essential for determining the stage of the tumor and setting a therapeutic plan. there are different methods for isolating lymph nodes in surgical specimens of breast cancer in the pathology depar...

Cervical lymphadenopathy is a common presentation of nasopharyngeal carcinoma (NPC). It can be present in the classical location of the level II or VI lymph nodes or at any other levels of the lymph nodes in the neck. NPC should be suspected when a patient presents with cervical lymphadenopathy and conductive hearing loss. A thorough endoscopic assessment of the nasopharynx should be performed ...

background in the diagnosis of malignant lymph nodes (lns) and staging of lung cancer, sampling of mediastinal and hilar lns is essential. mediastinoscopy is known as the gold standard. convex probe (cp) endobronchial ultrasound (ebus)-guided transbronchial needle aspiration (tbna) is a noninvasive and highly sensitive diagnostic method in mediastinal and hilar ln sampling. objectives evaluatin...

lymph node dissection is of prime importance for accurate staging of colorectal carcinomas. since a great number of small lymph nodes are missed in the traditional method, several fat clearing solutions have been introduced for easier detection of smaller lymph nodes. in this study we evaluated the efficacy of a new fat clearing solution so-called lymph node revealing solution (lnrs) in colecto...

In most cancers of epithelial origin, metastases to the lymph nodes constitute the most important prognostic factor and are predictive of the results of the surgical and adjuvant therapies. Data on the lymph node status allows to design an appropriate treatment plan. Despite advances in gynecologic oncology the importance of lymph node micrometastases in cervical cancer especially in nonsentine...

OBJECTIVE The purpose of this study is to elucidate the usefulness of magnetic resonance imaging (MRI) and positron emission tomography (PET) for the detection of parametrial involvement and lymph node metastasis in patients with cervical cancer. METHODS Thirty-six patients with cervical cancer were retrospectively enrolled. MRI and PET scans were performed for all patients within a week befo...