Neurofibroma is an autosomal dominant disorder which has major criteria such as hyperpigmentation (cafe-au lait spots), cutaneous and subcutaneous tumors and bone deformities. In this report, a case of multifocal intraosseous neurofibroma in a 16-year-old male with right facial asymmetry, multiple unerupted maxillary posterior teeth and a previous history of infratemporal and orbital neurofibro...

A 77-year-old woman was referred to our outpatient clinic because of bluish-gray pigmentation of the facial skin and lower legs (figures 1A and 1B). Her medical history revealed hypertension, hypercholesterolaemia and chronic obstructive pulmonary disease Global Initiative for Chronic Obstructive Lung Disease (Gold) classification 3. Home medication included metoprolol, barnidipine, irbesartan,...

There has been a proliferation of treatments for facial rejuvenation but, curiously, the use of such treatments on other areas of the body has not been widely investigated. The clinical effects of treating photodamaged skin of the neck and anterior chest area (décolletage) with a proprietary copper zinc malonate lotion and a proprietary 4% hydroquinone cream (twice daily), plus tretinoin cream ...

Melasma is a commonly acquired hypermelanosis that affects sun-exposed areas of the skin, with frequent facial involvement. Its histologic manifestations are evident in the epidermis, extracellular matrix, and dermis. In addition to epidermal pigmentation, pathologic findings of melasma include extracellular matrix abnormality, especially solar elastosis. The disrupted basement membrane has bee...

Spontaneous facial self-touch gestures (sFSTG) are performed manifold every day by every human being, primarily in stressful situations. These movements are not usually designed to communicate and are frequently accomplished with little or no awareness. The aim of the present study was to investigate whether sFSTG are associated with specific changes in the electrical brain activity that might ...

BACKGROUND It has been reported that intense pulsed light is efficacious for rejuvenation of photoaged skin, specifically the improvement of appearance of telangiectases and solar lentigines. OBJECTIVE The objective was to define the treatment variables for photodamaged facial skin using a newer intense pulsed light system. METHODS Twenty-three female subjects received three treatments usin...

introduction h syndrome (omim 612391) is an autosomal recessive disease with some features such as hyperpigmentation, hypertrichosis, heart anomalies, hepatosplenomegaly, hearing deficit, hypogonadism, short stature, flexion contracture of fingers and toes and hypertriglyceridemia. case presentation a 17-year-old boy with hyperpigmented, hypertrichotic and indurated seborrheic keratosis-like cu...