نتایج جستجو برای: central nervous system agents

تعداد نتایج: 2842552  

Journal: :Topics in magnetic resonance imaging : TMRI 2011
Carlos Torres Roy Riascos Ramon Figueroa Rakesh K Gupta

Tuberculosis (TB) has shown a resurgence in nonendemic populations in recent years and accounts for 8 million deaths annually in the world. Central nervous system involvement is one of the most serious forms of this infection, acting as a prominent cause of morbidity and mortality in developing countries. The rising number of cases in developed countries is mostly attributed to factors such as ...

2016

Lipoprotein and cholesterol metabolism in the brain involves metabolic pathways that are regulated independently of those in the peripheral circulation and tissues. The blood–brain barrier (BBB) restricts plasma lipids, including cholesterol and plasma lipoproteins, from entering or leaving the central nervous system (CNS). In the CNS, cholesterol is synthesized by astrocytes, oligodendrocytes,...

Maryam Moghadam Qaeni, Sepideh Mansoori Majoofardi, Zahra Sheidae Mehne,

Systemic Lupus Erythematosus (SLE) is a complex clinical syndrome which its components are less clearly recognized and includes heterogeneous demonstrations engaging both central and peripheral nervous system along with disabling effects. This disease is called "thousand faces" due to these heterogeneous demonstrations. This gap exists while 75% of adults and children with SLE may dea...

Modarres Mousavi, Mostafa , Sahab Negah, Sajad , Aligholi , Hadi , Eshaghabadi , Arezou , Kazemi , Hadi , Khaksar , Zabihollah , Mohammad Sadeghi , Shahin ,

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Journal: :Duodecim; laaketieteellinen aikakauskirja 1979
J C Garcia-Monco

Involvement of the central nervous system (CNS) by Mycobacterium tuberculosis, particularly meningitis, is the most severe form of tuberculous infection. Parenchymal CNS involvement can occur in the form of tuberculoma or, more rarely, abscess. Although surgery was initially advocated as the mainstay of therapy, more recent evidence suggests that parenchymal forms of CNS tuberculosis can be cur...

Journal: :Journal of the National Comprehensive Cancer Network : JNCCN 2008
Louis Burt Nabors Mario Ammirati Philip J Bierman Henry Brem Nicholas Butowski Marc C Chamberlain Lisa M DeAngelis Robert A Fenstermaker Allan Friedman Mark R Gilbert Deneen Hesser Matthias Holdhoff Larry Junck Ronald Lawson Jay S Loeffler Moshe H Maor Paul L Moots Tara Morrison Maciej M Mrugala Herbert B Newton Jana Portnow Jeffrey J Raizer Lawrence Recht Dennis C Shrieve Allen K Sills David Tran Nam Tran Frank D Vrionis Patrick Y Wen Nicole McMillian Maria Ho

Primary and metastatic tumors of the central nervous system are a heterogeneous group of neoplasms with varied outcomes and management strategies. Recently, improved survival observed in 2 randomized clinical trials established combined chemotherapy and radiation as the new standard for treating patients with pure or mixed anaplastic oligodendroglioma harboring the 1p/19q codeletion. For metast...

Journal: :Hematology. American Society of Hematology. Education Program 2002
Andrew Lister Lauren E Abrey John T Sandlund

Central nervous system involvement with malignant lymphoma whether primary or secondary is an uncommon but not rare complication observed in the management of patients with hematological malignancy. Its importance lies in the considerable morbidity and mortality with which it is associated and the inadequacy of therapy. In Section I, Dr. Lauren Abrey addresses the totality of the problem of pri...

Journal: :Neuroimaging clinics of North America 2010
Ashley H Aiken

This article outlines a practical imaging approach to CNS infection and reviews 5 basic imaging patterns commonly seen: (1) extra-axial lesion, (2) ring-enhancing lesion, (3) temporal lobe lesion, (4) basal ganglia lesion, and (5) white matter abnormality. Opportunistic infections in the setting of HIV are also discussed within the context of these 5 basic imaging patterns. Characteristic imagi...

Journal: :Emergency medicine clinics of North America 2009
David Somand William Meurer

Central nervous system infections have long been recognized as among the most devastating of diseases. This article describes the changing pattern and epidemiology of a variety of common central nervous system infections, including meningitis, encephalitis, and brain abscesses, and reviews pathophysiology and the most current approach to clinical diagnosis, treatment, and disposition from the e...

Journal: :Current opinion in rheumatology 2009
Rula A Hajj-Ali Leonard H Calabrese

PURPOSE OF REVIEW In the past decade, primary and secondary central nervous system (CNS) vasculitides have been more commonly diagnosed and recognized than previously. With the increasing awareness of these disorders, it is crucial for the treating physician to differentiate between causes of CNS vasculitis and to recognize their marked clinical and pathophysiological heterogeneity. This review...

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