background and purpose: leukemia is the most prevalent type of cancer in children and its prognostic factors vary in different geographic locations. the aim of this study was to estimate the 5 years survival rate of children suffering from leukemia in kerman, iran and to investigate the factors which might influence it. materials and methods: this was a cohort study conducted on patients with a...

background: stem cell factor (scf) is a transcriptional factor which plays crucial roles in normal proliferation, differentiation and survival in a range of stem cells. objective: the aim of the present study was to examine the proliferation effect of different concentrations of scf on expansion of human endometrial cd146+ cells. materials and methods: in this experimental study, total populati...

Introduction: 90% of the tumors in the head and neck are squamous-cell carcinomas (HNSCC), which have overall 5- year survival rate between 50% -60%. CD44 has been shown to be associated with the prognosis.  Materials and Methods: Biopsy specimens of 51 patients with oral tongue SCC were evaluated by Immunohistochemistry (IHC) for the CD44 antibody.  Results: There was no significant correlatio...

Esophageal cancer is a lethal disease with poor survival rate. It is necessary to determine the extension, and the stage of the tumor to predict the outcome of patients. Of the two common pathologic types, squamous cell carcinoma is still the most common form, and adenocarcinoma is the leading one. Early diagnosis and radical treatment of esophageal cancer, regardless of tumor spreading, increa...

The standard therapy for thyroid cancer is total or near total thyroidectomy, followed by the administration of radioactive iodine for remnant ablation or residual disease. Patients with radioiodine therapy are predisposed to second malignant neoplasms in organs such as central nervous system (CNS), breast, prostate, kidney, bone marrow, salivary gland, and digestive tract. Exposure to carcinog...

the protective effects of rheum tanguticum polysaccharide 1 (rtp1), which is extracted from the chinese traditional medicine rheum tanguticum, on radiation-induced intestinal mucosal injury was investigated. rat intestinal crypt epithelial cells (iec-6 cells) and sprague-dawley rats were each divided into control, irradiated and rtp1-pretreated irradiated groups. after irradiation, cell surviva...

the aim of this study was to evaluate antitumour activity of the roots of hibiscus tiliaceus linn. against dalton’s ascitic lymphoma (dal) in swiss albino mice. a significant enhancement of mean survival time (mst) of h. tiliaceus treated tumour bearing mice was found with respect to control group. h. tiliaceus treatment was found to enhance peritoneal cell counts. when these h. tiliaceus treat...

This study was intended to investigate the effectiveness of static magnetic field on the growth of Escherichia coli (E. coli) provided from two sources, the urine samples of patients with urinary tract infections and the reference strain E. coli ATCC 25922. Bacterial samples in Nutrient Broth were subjected to a range of magnetic intensities (2, 4, 6, 9, 14, 16, 18, and 20 mT) at various exposu...

Introduction: Growth, proliferation, survival, and differentiation are the prominent characteristics of cells, which are affected by cancer. Epidermal growth factor receptor (EGFR) plays a pivotal role in the effective control of these features. Given the significance of EGFR signaling pathway in non-small cell lung cancer (NSCLC), EGFR expression is influential on these cell characteristics. I...