The bacillus of glanders may be so modified in virulence as to produce experimentally lesions differing widely in their histological features. The highly virulent culture causes primary necrosis and disintegration of the tissue followed by the invasion of the injured area by polymorphonuclear leucocytes. The bacilli of moderate virulence give rise to a primary lesion of an acute inflammatory na...

The main objectives of this study were (a) to evaluate the in vitro performance of the rapid disintegration tablets as a way to improve the solid dispersions and (b) to study the in vivo pharmacokinetics of the albendazole modified formulation in dogs. Rapid disintegration of tablets seems to be a key factor for efficiency of solid dispersions with regard to improvement of the albendazole bioav...

An explicit evaluation of the spin asymmetry of the deuteron and the associated GDH sum rule is presented which includes disintegration, single and double pion and eta production. For the GDH integral a large cancellation is found between the disintegration channel and the meson production channels. Furthermore, first results for the contribution of the disintegration channel to the generalized...

The notions of disintegration and Bayesian inversion are fundamental in conditional probability theory. They produce channels, as conditional probabilities, from a joint state, or from an already given channel (in opposite direction). These notions exist in the literature, in concrete situations, but are presented here in abstract graphical formulations. The resulting abstract descriptions are ...

a research program was conducted on different clay-bearing rocks selected from the ilam, sarpol-e zahab and tajarak regions (iran) to predict their slaking characteristics. the new durability apparatus (nested mesh drums) separates disintegrated particles varying from > 25.4 to < 2 mm as the drums were rotated. on the basis of the particle size distribution, the disintegration ratio (dr) was us...

The USP General Chapter <2040> Disintegration and Dissolution of Dietary Supplements introduced a rupture test as a performance test of soft-shell capsules. Traditionally, the disintegration test was used for determining the disintegration time of all solid oral dosage forms. The aim of this investigation was to investigate differences between the rupture test and the disintegration test using ...