نتایج جستجو برای: cd16

تعداد نتایج: 2438  

Journal: :Blood 2000
M Sjölinder L Stenke B Näsman-Glaser S Widell J Doucet P J Jakobsson J A Lindgren

Elevated leukotriene (LT)C(4) synthase activity was observed in peripheral blood granulocyte suspensions from patients with chronic myeloid leukemia (CML). Magnetic cell sorting (MACS) with CD16 monoclonal antibodies (mAbs), which were used to fractionate granulocytes from CML patients and healthy individuals, yielded highly purified suspensions of CD16(+) neutrophils. The purity of these cell ...

Journal: :Genetics and molecular research : GMR 2015
X F Ma F L Xu L F Gao Y X Wang Z B Pan

We investigated the effect of age on the expression of immune molecules [ANA, C4, double stranded DNA (dsDNA), CD16/32, CD19, CD3, and CD64], urine protein, and pathology in mice with chronic graft-versus-host disease (cGVHD) lupus nephritis (LN), and their relationship with reactivity index score. Mouse models of cGVHD LN were established, and mice were randomly divided into four aged-based gr...

2018
Gong Chen Ya-Chi Chen Bernhard Reis Anton Belousov Lori Jukofsky Christine Rossin Axel Muehlig Chao Xu Laurent Essioux Toshihiko Ohtomo Laura Di Laurenzio Oscar Puig Ray Lee

Background Codrituzumab, a monoclonal antibody targeting an oncofetal protein glypican-3 (GPC3) expressed on cell surface of hepatocellular carcinoma (HCC) induces antibody-dependent cellular cytotoxicity (ADCC) and inhibits tumor growth in preclinical studies. Based on this mechanism, tumor GPC3 expression and CD16 expression on NK cells, which are the effector cells of ADCC, were investigated...

Journal: :Blood 2007
Diego Piccioli Simona Tavarini Erica Borgogni Veronica Steri Sandra Nuti Chiara Sammicheli Monia Bardelli Daniela Montagna Franco Locatelli Andreas Wack

Human blood contains 2 populations of dendritic cells (DCs): plasmacytoid and myeloid (mDC). mDCs are subdivided into 3 subsets using the surface markers CD16, CD1c, and BDCA-3. Their role as pathogen sentinels and adjuvant targets was tested by phenotypic and functional analysis. We show that mDC subsets are immature and express mRNA for most toll-like receptors (TLRs), except for TLR3 in CD16...

2017
Xiao Han Jing Ruan Wei Zhang Daobin Zhou Dongsheng Xu Qiang Pei Mingqi Ouyang Mengxuan Zuo

BACKGROUND Recent studies have suggested that variables related to host adaptive immunity and the tumor microenvironment may predict the outcome in patients with non-Hodgkin's lymphoma. This study was undertaken to determine the prognostic value of peripheral blood leucocyte subpopulations in diffuse large-B-cell lymphoma patients. METHODS We prospectively analyzed the 16 leukocyte subpopulat...

Journal: :Inflammatory bowel diseases 2007
Olof Grip Anders Bredberg Stefan Lindgren Gunnel Henriksson

BACKGROUND Circulating monocytes may be subdivided according to the presence or absence of the Fcgamma receptor CD16 and the neural cell adhesion molecule CD56. Monocytes classified into these subpopulations are characterized by distinct phenotypic and functional features. We hypothesized that patients with active Crohn's disease differ in their peripheral monocyte subpopulations. METHODS Usi...

Journal: :Acta medica Okayama 2007
Ryusuke Yano Masahiro Yamamura Katsue Sunahori Kouji Takasugi Jiro Yamana Masanori Kawashima Hirofumi Makino

CD16+ monocytes, identified as a minor population of monocytes in human peripheral blood, have been implicated in several inflammatory diseases, including rheumatoid arthritis (RA). Fractalkine (FKN, CX3CL1), a member of the CX3 C subfamily, is induced by pro-inflammatory cytokines, while a receptor for FKN, CX3CR1, is capable of mediating both leukocyte migration and firm adhesion. Here, we in...

2016
B. Thaler P. J. Hohensinner K. A. Krychtiuk P. Matzneller L. Koller M. Brekalo G. Maurer K. Huber M. Zeitlinger B. Jilma J. Wojta W. S. Speidl

Human monocytes are a heterogeneous cell population, which can be divided into a classical (CD14++CD16-), a non-classical (CD14+CD16+), and an intermediate (CD14++CD16+) subset. We hypothesized that low-grade inflammation may differentially affect monocyte subsets. We used a human lipopolysaccharide (LPS) infusion model to mimic low-grade inflammation to identify, which monocyte subsets are pre...

2014
Lis R. V. Antonelli Fabiana M. S. Leoratti Pedro A. C. Costa Bruno C. Rocha Suelen Q. Diniz Mauro S. Tada Dhelio B. Pereira Andrea Teixeira-Carvalho Douglas T. Golenbock Ricardo Gonçalves Ricardo T. Gazzinelli Mary M. Stevenson

Infection with Plasmodium vivax results in strong activation of monocytes, which are important components of both the systemic inflammatory response and parasite control. The overall goal of this study was to define the role of monocytes during P. vivax malaria. Here, we demonstrate that P. vivax-infected patients display significant increase in circulating monocytes, which were defined as CD14...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید