نتایج جستجو برای: cd105

تعداد نتایج: 1193  

Journal: :Tumori 2012
Simona Gurzu Anca Maria Cimpean Judit Kovacs Ioan Jung

The aim of the study was to compare the simple immunostains performed with CD31, CD34 and CD105 antibodies, with double-labeling immunostains realized with CD105 (endoglin) and smooth muscle actin antibodies in colorectal carcinomas. Fourty colorectal carcinoma surgical specimens were immunohistochemically studied. Quantification of microvessel density was realized at 400× magnification, in the...

2011
Cristina Grange Marta Tapparo Federica Collino Loriana Vitillo Christian Damasco Maria Chiara Deregibus Ciro Tetta Benedetta Bussolati Giovanni Camussi

Recent studies suggest that tumor-derived microvesicles (MV) act as a vehicle for exchange of genetic information between tumor and stromal cells, engendering a favorable microenvironment for cancer development. Within the tumor mass, all cell types may contribute to MV shedding, but specific contributions to tumor progression have yet to be established. Here we report that a subset of tumor-in...

Journal: :The Journal of rheumatology 2011
Tamara Hermida-Gómez Isaac Fuentes-Boquete Maria José Gimeno-Longas Emma Muiños-López Silvia Díaz-Prado Francisco Javier de Toro Francisco Javier Blanco

OBJECTIVE To quantify cells expressing mesenchymal stem cell (MSC) markers in synovial membranes from human osteoarthritic (OA) and healthy joints. METHODS Synovial membranes from OA and healthy joints were digested with collagenase and the isolated cells were cultured. Synovial membrane-derived cells were phenotypically characterized for differentiation experiments using flow cytometry to de...

Journal: :Journal of cellular biochemistry 2009
M C Arufe A De la Fuente I Fuentes-Boquete Francisco J De Toro Francisco J Blanco

Mesenchymal stem cells (MSCs) have the capacity to differentiate into several cell lineages, some of which can generate bone, cartilage, or adipose tissue. The presence of MSCs in the synovial membrane was recently reported. Data from comparative studies of MSCs derived from various mesenchymal tissues suggest that MSCs from synovial membranes have a superior chondrogenesis capacity. Previous c...

Background and Objectives: Angiogenesis is essential for growth and metastasis of solid malignancies. Tumor vessel count and expression of vascular endothelial growth factor (VEGF), a potent angiogenic factor, have been associated with prognosis. This study was designed to assess vessels density by using CD31 and CD105 (Endoglin) and their correlation with expression of VEGF and prolif...

Introduction: There are few studies investigating the role of neoangiogenesis in biological behavior of salivary gland tumors. CD105 expression has demonstrated greater accuracy for detecting new vessel formation compared with other pan-endothelial molecules. This study aimed to assess and compare intratumoral Micro-Vessel Density (MVD) through using immunohistochemichal expression of CD105 bio...

Journal: :Indonesian Journal of Obstetrics and Gynecology 2018

Journal: :Cancer research 2002
Fumihiro Tanaka Shinya Ishikawa Kazuhiro Yanagihara Ryo Miyahara Yozo Kawano Mio Li Yosuke Otake Hiromi Wada

Angiopoietin (Ang)-1 and -2 have been recently identified as potent angiogenic factors which function in concert with vascular endothelial growth factor (VEGF), but no detailed clinical study on Ang expression has been reported. To assess the clinical significance of Ang expression in non-small cell lung cancer (NSCLC), a total of 236 patients with pathological stage-I-IIIA disease were retrosp...

Journal: :Journal of the National Cancer Institute 2011
Sandy Azzi Stefania Bruno Julien Giron-Michel Denis Clay Aurore Devocelle Michela Croce Silvano Ferrini Salem Chouaib Aimé Vazquez Bernard Charpentier Giovanni Camussi Bruno Azzarone Pierre Eid

BACKGROUND Many renal cancer patients experience disease recurrence after immunotherapy or combined treatments due to persistence of cancer stem cells (CSCs). The identification of reliable inducers of CSC differentiation may facilitate the development of efficient strategies for eliminating CSCs. We investigated whether interleukin 15 (IL-15), a regulator of kidney homeostasis, induces the dif...

2011
David Pretzel Stefanie Linss Steffen Rochler Michaela Endres Christian Kaps Saifeddin Alsalameh Raimund W Kinne

INTRODUCTION Mesenchymal stem cells (MSC) are highly attractive for use in cartilage regeneration. To date, MSC are usually recruited from subchondral bone marrow using microfracture. Recent data suggest that isolated cells from adult human articular cartilage, which express the combination of the cell-surface markers CD105 and CD166, are multi-potent mesenchymal progenitor cells (MPC) with cha...

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