A major environmental concern due to dispersal of industrial and urban wastes generated by human activities is the contamination of soil. The release of heavy metals into the terrestrial ecosystem is a major problem. Accumulation of heavy metals in environment and particularly in soil is a serious environmental concern, as the accumulated heavy metal ions can find their way into living organism...

Aspartame is an artificial sweetener in foods and beverages. Continuous use of aspartame will result oxidative stress the liver. So we need antioxidants from outside body such as periwinkle leaves.This study aims to determine effect leaves (Catharanthus roseus L) on aspartame-induced liver histology. This used 24 male mice divided into 4 groups, namely negative control (K-) without treatment; P...

Vindoline and its analogues are important constituents of the Madagascan periwinkle Catharanthus roseus, and some of them are valuable chemotherapy drugs used in treatment for some types of cancer, including leukaemia, lymphoma, breast and lung cancer. The search for semi-synthetic congeners of natural substances is still an important task for organic chemistry. In this communication we report ...

We have isolated fifty-two endophytic fungi (AA-CRL-1 to AA-CRL52) from the leaves of Catharanthus roseus plants collected from different parts of Pune (Maharashtra, India). These endophytic fungi represented different genera and were screened for vinca alkaloids production using TLC and ESI-MS analysis. Out of the 52 endophytic fungal cultures screened, the endophytic culture AA-CRL-20 was fou...

The water extract, methanol, free flavonoids and bound flavonoids of Allium sativum, Cymbopogon martinii and Catharanthus roseus were screened for their antimycotic activities using disc diffusion method. They were tested against dermatophytes, isolated from patients having tinea infection. The activities of the extracts were compared with the standard antibiotics. The bound flavonoid extracts ...

Apocynaceae is a large family of tropical trees, shrubs and vines with most species producing white latex. Major metabolites of species are triterpenoids, iridoids, alkaloids and cardenolides, which are known for a wide range of biological and pharmacological activities such as cardioprotective, hepatoprotective, neuroprotective, anti-inflammatory, anticancer and antimalarial properties. Prompt...