The numerical simulation has made tremendous advances in investigating the blood flow phenomenon through elastic arteries. Such study can be useful in demonstrating the disease progression and hemodynamics of cardiovascular diseases such as atherosclerosis. In the present study, patient specific case diagnosed with partially stenosed complete right ICA and normal left carotid bifurcation withou...

The ability to noninvasively detect regional dynamic myocardial damage related to action potentials and mechanical properties affected by heart disease is of great clinical importance. Though there are invaluable clinical tools for diagnosis of a broad range of cardiac conditions, such myocardial properties cannot be evaluated. We have previously shown that pulsive vibration occurs on the myoca...

LIE pulmonary second sound plays an important role in the clinical diagnosis of congenital and acquired heart diseases. Since phonocardiographic recordings from the chest wall present the pulmonary valve sound as part of a composite of sounds produced by 2 valves of the heart, it was our interest to demonstrate the pulmonary sound by direct phonocardiography. Cardiac sounds and murmurs heard an...

OBJECTIVES We compared in vivo 3.0-T magnetic resonance (MR) images of the carotid artery wall in piglets to intima-media thickness measurements of similar carotid segments by B-mode ultrasound (US) and histology to define the corresponding anatomical tissue characteristics and accuracy of carotid MR images. BACKGROUND Carotid MR is increasingly used for the assessment of cardiovascular risk ...

BACKGROUND AND PURPOSE Mechanical stresses on the arterial wall participate in the pathogenesis of atherosclerosis as local factors. The relationships between local mechanical forces and risk factors for atherosclerosis were investigated. METHODS Mechanical forces on the arterial wall were evaluated in the carotid artery in 117 patients with risk factors for atherosclerosis including hyperten...

Carotid artery intima-media thickness (IMT) increases with advancing age in humans. The underlying mechanism of this increase is unknown, but data from animal studies suggest that a chronic increase in local distending pressure can act as a stimulus. To test this hypothesis, we studied a total of 129 healthy normotensive, nonobese, nonsmoking men aged 18 to 77 years. Brachial systolic blood pre...

Background: The carotid artery is an important blood vessel in the human body. Its ruptures caused by accidents can be lethal cases without timely treatment. Currently, successful rescue cases have rarely been reported, hence we present the following case. Case presentation: A patient who was a 46-year-old male admitted due to left neck trauma that lasted almost a day. The CT angiography (CTA) ...

Carotid arteries are a common site of atherosclerotic lesion development. Computational fluid dynamics models suggest that flow disturbances associated with stenosis can contribute to the initiation and progression of vascular wall pathologies. The main goal of this study is to present an investigation on the overall influence of assumptions regarding the outflow boundary conditions in hemodyna...