In the majority of cases, acromegaly is sporadic. However, it can also occur in a familial setting as a component of MEN-1, MEN-4, Carney complex (CNC) or as the extremely rare syndrome of isolated familial somatotropinoma (IFS), the latter belonging to familial isolated pituitary adenomas (FIPA). The diagnosis of IFS is based on the recognition of acromegaly/gigantism in at least two family me...

Myxoma is a benign connective tissue tumor that is most commonly found in the heart. Because myxoma of the external ear is extremely rare, its diagnosis may be easily delayed or it may be misdiagnosed as another disease. Moreover, because it can be a part of Carney complex (autosomal dominant syndrome), its correct diagnosis is very important. We experienced a 10-year-old girl who had a mass on...

© 2013 The Authors. doi: 10.2340/00015555-1366 Journal Compilation © 2013 Acta Dermato-Venereologica. ISSN 0001-5555 The triad exophthalmus, pre-tibial myxoedema, osteoarthropathia (EMO syndrome) was first described by Thomas in 1933 and represents a rare condition occurring in patients with Graves’ disease (1). Graves’ disease is a common autoimmune disorder of the thyroid gland due to a produ...