AIM To assess the efficacy and safety of fibrin sealant for closure of mucosal penetration at the cardia during peroral endoscopic myotomy (POEM). METHODS Twenty-four patients who underwent POEM and experienced mucosal injury of the cardia during the procedure were retrospectively identified. Of the 24 patients, 21 had mucosal penetration and 3 had only slight mucosal damage without penetrati...

BACKGROUND/AIM Most studies of esophageal and gastric adenocarcinomas have shown a very high rate of p53 gene mutation and/or protein overexpression, but the influence of the tumour site upon the frequency of p53 protein expression has not been evaluated (gastroesophageal junction, Barret's esophagus, and antrum). The aim of our study was to analyze the correlation between the selected clinico-...

We describe here a case of 36-year-old man with a hepatic cavernous hemangioma that was misdiagnosed as a gastric submucosal tumor (SMT) with endoscopic ultrasound (EUS) and CT scan. On gastroscopy, a submucosal tumor was found on the cardia of the stomach. Based on EUS and abdominal CT scan, the lesion was diagnosed as a gastric duplication cyst. The patient underwent gastroscopy after receivi...

RESEARCH DESIGN AND METHODS—This was an ancillary study to the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Habitual sleep duration and fragmentation were estimated from 6 days of wrist actigraphy collected in 2003–2005. Insomnia was defined as self-reported difficulty falling asleep or waking up in the night three or more times per week plus average sleep efficiency of ,80%...

CONTEXT Non-islet-cell-tumor-induced hypoglycemia (NICTH) is caused on rare occasions by secretion of insulin from tumor cells that are reported to have a single tissue origin. CASE REPORT A 67-year-old male patient had cardia adenocarcinoma and concomitant lung adenocarcinoma with extensive metastases and repeated episodes of intractable hypoglycemia. Immunohistochemical staining for insulin...

Achalasia cardia is a motility disorder characterised by failure of relaxation the lower oesophageal sphincter (LES) and associated with lack peristalsis in body oesophagus. The mainstay treatment achalasia to reduce LES pressure improve emptying gravity. LHM still considered gold standard against which other methods are compared. records all patients who underwent surgery for between August 20...

sory, or aberrant pancreas is a pancreatic tissue without anatomic and vascular continuity within the main body of the gland, and is most commonly found in the antrum of the stomach, duodenum, or proximal jejunum (1, 2). Ectopic pancreas in the proximal stomach has been rarely reported (3). However, the coexistence of two ectopic pancreases at the gastric cardia and antrum in a patient has not ...

Background: The reliability of methods for identifying the circumferential position small lower esophageal lesions is unknown. We prospectively investigated a new method that presents lesion positions as times on clock face. Methods: Eighty-seven patients were consecutively examined by endoscopy. After observing esophagus, an endoscope was inserted into stomach and fixed, greater curvature fold...

Achalasia cardia is one of the common causes of motor dysphagia. Though the disease was first described more than 300 years ago, exact pathogenesis of this condition still remains enigmatic. Pathophysiologically, achalasia cardia is caused by loss of inhibitory ganglion in the myenteric plexus of the esophagus. In the initial stage, degeneration of inhibitory nerves in the esophagus results in ...