Objective(s) Shark Liver Oil (SLO) is an immunomodulator. Macrophages play a key role in host defense against pathogens like fungi. Candida albicans have mechanisms to escape immune system. We determined the effect of killed-Candida on the in vitro viability of macrophages and the effect of SLO on augmentation of this potency. Materials and Methods Peritoneal macrophages were separated and c...

The growing number of fungal infections, coupled with emerging resistance to classical antifungal agents, has led to the development of new agents, among them voriconazole. Susceptibility to voriconazole was tested by using two microdilution techniques: the reference method described in National Committee for Clinical Laboratory Standards document M27-A2 and a colorimetric method, Sensititre Ye...

The new colorimetric Vitek 2 YST card was evaluated for identification of yeasts (136 strains) with respect to the influence of different source media. The Vitek 2 YST card achieved satisfactory results for all yeast species tested, with the exception of Candida guilliermondii, Candida norvegensis, Candida parapsilosis, Candida rugosa, and Candida tropicalis. After simple additional tests, 93.7...

The effect of gentian violet against Candida albicans and non-Candida albicans biofilms formed on polymethylmethacrylate strips was evaluated using a dry weight assay and confocal laser scanning microscopy. The ability of gentian violet to inhibit Candida albicans germination was also assessed. Gentian violet activity against Candida biofilms was demonstrated by a reduction in dry weight, disru...

We report on the isolation of Candida nivariensis from a renal transplant patient with persistent candiduria. Biochemical profiling misidentified isolates as Candida glabrata (3/5) and Candida inconspicua (2/5). All isolates produced white colonies on CHROMagar(™) Candida medium. Internal transcribed spacer (ITS) ribosomal gene sequence analysis and MALDI-TOF-MS analysis (Bruker Biotyper(™) 2.0...

abstract background: the disk diffusion method for identification of yeasts species was performed based on different but distinct susceptibilities of yeasts spp. to chemicals: janus green, ethidium bromide, 2,3,5-triphenyltetrazolium chloride, brilliant green, cycloheximide and rhodamine 6g. methods: atotal of 568 iranian soldiers went under study for isolation and identification of yeast speci...

conclusions candida albicans was the major pathogen associated with candidiasis of the female genital tract in patients in chongqing. the results of the antifungal sensitivity of the isolates suggest that it is important for clinicians to administer appropriate antifungals for the treatment of candida spp. infections. background vulvovaginal candidiasis is defined as vulvovaginitis associated w...

conclusions knowledge about the susceptibility patterns of colonized candida spp. can be helpful for clinicians to manage pediatric patients with neutropenia. in this study, caspofungin was the most effective antifungal agent against the colonized candida spp. followed by conventional amphotericin b. patients and methods in this study 188 children with neutropenia were recruited, fungal surveil...

The frequent clinical observation of the association of diabetes mellitus and candidiasis'z prompted an investigation of the effect of alloxan diabetes on experimental infections in mice caused by Candida albicans, Candida tropicalis, Candida guilliermondii, and Candida parapsilosis. The results of this investigation reveal that alloxan diabetes enhances, in the mouse, experimental infections c...