Providing effective and tolerable cancer treatment for the growing number of older adult patients who have cancer will require an understanding of the role of aging, comorbidity, functional status, and frailty on treatment outcomes. The incorporation of CGA into the care of older patients who have cancer will ensure that the heterogeneity of this population is considered in the development of t...

abstract background: tamoxifen, a synthetic anti-estrogen agent, is administered as an adjuvant treatment in breast cancer. since various studies have indicated that tamoxifen can change some hormones and bound globolines, controversial results have been achieved using this medicine on thyroid functional tests (tft). the present study was conducted to investigate the effects of tamoxifen on tft...

nanotechnology has slowly but steadily revolutionized the diagnosis, imaging and treatment of cancer. detecting cancer at earliest stages, locating the tumor at different areas in the body and specific delivery of the drugs to malignant cells including surgically inaccessible tumors are the core areas of medical and pharmaceutical research across the world. in this endeavour, nanodevices have e...

Nanoparticles have been at the center of research focus as a new promising material for the treatment of cancer in recent years. Although many chemotherapy drugs for cancer treatment are available, their potential toxicity is the main point of concern. On the other hand, the conventional chemotherapeutic approach has not been found to be very efficient in colorectal cancer (CRC) as the drug mol...

nanotechnology is the engineering of functional systems at the molecular scale which may exert a revolutionary impact on cancer diagnosis and therapy. nanotechnology is being applied to cancer in two broad areas: i) the development of nanovectors such as nanoparticles which can be loaded with drugs or imaging agents and then targeted to tumours, and ii) high-throughput nanosensor devices for de...

background: electrochemotherapy is a relatively new technique in the treatment of skin metastases that are not amenable to conventional therapy. its use in breast cancer is now established in many european centers. methods: published literature of electrochemotherapy in terms of its scientific basis, current clinical practice of breast cancer treatment providers, as well as the future direction...

Prostate cancer is the most common and second leading cause of death among men in the world. Nowadays, radiotherapy has been known as one of the most affecting methods for prostate cancer treatment. Nevertheless, radiotherapy is accompanied by the concern of developing secondary cancers by the scattered radiation to the neighbor  organs at risk. Several studies have shown that secondary cancers...

synchronous cancer is referred to two or more histological distinct malignancies diagnosed during the same hospital admission. globally more than 1 million people get colorectal cancer yearly resulting in about 0.5 million deaths. vulvar cancer is the fourth most common gynecologic cancer (following the corpus uterine cancer, cancer of ovary and cervix) and comprises only 4 percent of malignanc...

background: recent advances in cancer treatment have resulted in an increased number of cancer survivors. fertility might be impaired by cancer itself or through gonadal damage as a consequence of radio-chemotherapy. damages to reproductive organs are seen in minimally upto 30% of cancer patients. the aim of the present study was evaluate the attitude of iranian oncologists toward fertility pre...