The fact that the development of breast cancer is linked to repeated or sustained exposure to high blood estrogen levels has raised obvious concern that reproductive hormones particularly estrogen, might increase the risk of breast cancer development. While, the general consensus is that overall; IVF is not associated with an increased risk for development of breast cancer, a recent report publ...

 Background: Breast cancer is the first leading cause of cancer-related death in women. Pesticides which are excessively used in northern Iran are one of the most important risk factors for breast cancer incidence. The cytochrome P450 1A1 (cyp1A1) is a key enzyme in xenobiotics metabolism and SNPs of its coding gene has been verified to be important in cancer susceptibility. The aim of thi...

Introduction: Diabetes is associated with an increased risk of cancer. Because of the metastatic nature of cancer, the survival of women with breast cancer is decreasing despite receiving various treatments such as chemotherapy, radiotherapy, etc. The aim of this study was to investigate the relationship between diabetes and the risk factors related to the survival of breast cancer patients. M...

background: one of the economic evaluation techniques involves calculation of willingness to pay (wtp) for a service to find out the value of that service from the clients’ perspective. this study estimated wtp for both breast cancer and osteoporosis screening and comparatively examined the contributing factors. in fact, the comparisons served to provide an exact analysis of individual attitude...

second to the cardiovascular disease, cancer is the main cause of death in iran. in this study some of the risk factors of breast cancer; especially the ones related to breastfeeding have been assessed. the study was a retrospective study of 100 women with breast cancer. the most important risk factors in breast cancer were number of children, age of mother on the first pregnancy. the result sh...

the tp53 gene is one of the most frequently mutated genes amongst human malignancies, particularly tp53 codon 72 polymorphism. furthermore, an association between the tp53 codon 72 variants and prostate cancer has been reported in several studies. although some studies have indicated an association between the tp53 arg/arg variant and an increased risk for prostate cancer, other studies have sh...

objective(s):leptin receptor (lepr) is a member of the class i cytokine receptor super-family that is known implicated in the initiation and progression of breast cancer. we have investigated the effect of q223r polymorphism on the breast cancer susceptibly in a sample of iranian subjects. materials and methods:we utilized a polymerase chain reaction (pcr) restriction fragment length polymorphi...

materials and methods twelve natural compounds jaceosidin, withaferin a, curcumin, epigallocatechin-3-gallate (egcg), artemisinin, gingerol, ursolic acid, ferulic acid, berberin, silymarin, resveratrol, and indol-3-carbinol were docked against e6 and e7 oncoproteins of high-risk hpv types 16 and 18 using a protein-ligand docking software called autodock4.2. results out of these 12 natural compo...