A major goal of Schwann cell (SC) transplantation for spinal cord injury (SCI) is to fill the injury site to create a bridge for regenerating axons. However, transplantation of peripheral nerve SCs requires an invasive biopsy, which may result in nerve damage and donor site morbidity. SCs derived from multipotent stem cells found in skin dermis (SKP-SCs) are a promising alternative. Regardless ...

Fanconi anemia (FA) is a multigenic recessive disease resulting in bone marrow failure and increased cancer susceptibility. Cells from FA patients and mouse models are sensitive to DNA interstrand crosslinks (ICLs) and FA mice are moderately sensitive to ionizing radiation (IR). Both kinds of damage induce DNA double strand breaks (DSBs). To date, nine genes in 11 complementation groups have be...

D eveloped at the Ecole Polytechnique Fédérale of Lausanne, Switzerland, Synchronous C++ has strong connections to the domains of concurrency, behavior analysis, and OO programming. Namely, sC++ contains a real-time kernel, lends itself to analysis by modern modeling and analysis theories, 1-3 and uses the same syntax for active objects as for passive ones. Understanding the relationship of con...

This document describes an application of the supervisory control (SC) methods to the synthesis of concurrent programs and presents current work on this topic of research. In particular, special attention is given to the development of software that applies SC to program synthesis. This work is motivated by the difficulties encountered in writing correct programs in the context of concurrency. ...

Dynamic voltage and frequency scaling (DVFS) is a powerful technique to reduce power consumption in a chip multiprocessor (CMP). To support DVFS in the multicore power delivery network, we integrate on-chip switched-capacitor (SC) DC-DC converters that can work with multiple conversion ratios to provide varying levels of Vdd supplies. We study the application of such SC converters in multicore ...

Campbell and Phenix (2009) observed retrieval-induced forgetting (slower response time) for simple addition facts (e.g., 3 + 4) immediately following 40 retrieval-practice blocks of their multiplication counterparts (3 × 4 = ?). A subsequent single retrieval of the previously unpracticed multiplication problems, however, produced an retrieval-induced forgetting (RIF) effect about twice as large...

The frontal eye field (FEF) contributes to directing visual attention and saccadic eye movement through intrinsic processing, interactions with extrastriate visual cortical areas (e.g., V4), and projections to subcortical structures (e.g., superior colliculus, SC). Several models have been proposed to describe the relationship between the allocation of visual attention and the production of sac...

In this talk, we discuss the principle of Minimum Description Length (MDL) for problems of statistical modeling. By viewing models as a means of providing statistical descriptions of observed data, the comparison between competing models is based on the stochastic complexity (SC) of each description. The Normalized Maximum Likelihood (NML) form of the SC (Rissanen 1996) contains a component tha...

Citation: Becker EA, Forney KA, Thayre BJ, Debich AJ, Campbell GS, Whitaker K, Douglas AB, Gilles A, Hoopes R and Hildebrand JA (2017) Habitat-Based Density Models for Three Cetacean Species off Southern California Illustrate Pronounced Seasonal Differences. Front. Mar. Sci. 4:121. doi: 10.3389/fmars.2017.00121 Habitat-Based Density Models for Three Cetacean Species off Southern California Illu...