Morphological transformation of Syrian hamster embryo cells was induced by direct exposure to some inorganic salts of nickel, cadmium, chromium, beryllium, and arsenic but not salts of iron, titanium, tungstate, zinc, aluminum, and nickel sulfide amorphous. Furthermore, no transfor mation was observed in untreated controls. Lethality, mdi cated by a reduction in cloning efficiency, occurred wit...