Cumin seeds (Cuminum cyminum L.) have been commonly used in food flavoring and perfumery. In this study, cumin essential oil (CuEO) extracted from seeds was employed to investigate the anti-inflammatory effects in lipopolysaccharide- (LPS-) stimulated RAW 264.7 cells and the underlying mechanisms. A total of 26 volatile constituents were identified in CuEO by GC-MS, and the most abundant consti...

Antibacterial activity of seed extracts of cumin (Cuminum cyminum L.) was investigated against 10 gram positive and gram negative bacteria. Disc diff usion method was used to test antibacterial activity. Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) were determined by using standard procedures. Th e highest (eff ective) inhibition zone of 16.67±0.47 mm was ...

Objective: The present study was to evaluate the dose-dependent effects of Cuminum cyminum (C. cyminum) on testicular gametogenic and androgenic activities in adult rat. Methods: The hydro-methanolic extract was administered orally at the dose of 30mg, 60mg and 120mg/100g body weight of rats for 28 days. The effects of the treatment on reproductive organs and testicular steroidogenesis were inv...

INTRODUCTION Coumarins exert many biological effects in humans, animals, and plants, which make the evaluation of their biological activities and study of their role in ethnomedicine highly valued. OBJECTIVES Here, we selected seven plants which have ethnopharmacological use as antimicrobial in Iraq and the aims were to quantify the two structural isomers bergapten and methoxsalen in their se...

introduction: nitric oxide (no) is a neuronal messenger molecule in the central nervous system, which is generated from l-arginine by nitric oxide synthase (nos) and involves in many important opioid-induced effects. our previous studies revealed that cuminum cyminum interestingly reduces morphine sensitization, tolerance and dependency in male mice. therefore, in the present study, the effect ...