Background: Efficacy of Centella asiatica on incision and burn wounds are not sufficiently known. In this study we evaluated[SYG1] wound healing activities of different extracts of Centella asiatica, namely hexane, ethyl acetate, methanol, and water extracts, in incision and partial-thickness burn wound models in rats. Results: On day 7 post-wounding, tensile strength of incision wound in all e...

background : bacterial infections in burn and wound patients are common and difficult to control. the aim of the current study was to evaluate the ability of full length oprf to elicit the production of protective igg in mice burn wound sepsis model against p. aeruginosa infection. methods : oprf protein was expressed and purified by ni-nta. the purified protein as used to immunize balb/c mice....

OBJECTIVE To validate the use of photographic burn wound assessment in evaluation of burn size and wound characteristics. METHODS Feasibility study of agreement between methods of measurement of burn size and characteristics, in patients admitted to the burn unit at Kamuzu Central Hospital (KCH), Malawi, over two months in 2011. Burn wounds were photographed and assessed clinically, concurren...

4,547 burn patients from 1983-1993 were reviewed by analysing the general data, mortality, and the causes of the death, and the mortality of 606 burn patients in different periods from 1958 to 1993. The purpose was to present some statistical and epidemiological data. The results showed: The incidence of burn injury in children, whose ages were less than 5 years, reached 36.2%, and the causes o...

Post-burn trauma significantly raises tissue serotonin concentration at the initial stages of injury, which leads us to investigate its possible role in post burn wound healing. Therefore, we planned this study to examine the role of serotonin in wound healing through in vitro and in vivo models of burn injuries. Results from in vitro analysis revealed that serotonin decreased apoptosis and inc...

An increasing number of burn wound infections are now due to fungi. Historically, therapy of fungal burn wound infections (FWI) consisted of debridement, topical antifungals and/or IV amphotericin B, negating the need to categorize disease further than fungal burn wound colonization (FWC) versus FWI. Newer antifungal agents have varying spectrums of activity, increasing the importance of identi...

conclusions despite the healing effects of aeo in burn wounds, petrolatum was more effective than aeo in post-laser wound. results our study indicated higher epithelial confluence and general wound appearance scores (p = 0.045 for both) and less erythema and edema on fifth day in petrolatum (p = 0.009 and p = 0.034, respectively). the results showed less crusting and erythema (p = 0.016 and p =...

INTRODUCTION Deep burn wounds undergo a dynamic process known as wound progression that results in a deepening and extension of the initial burn area. The zone of stasis is more likely to develop more severe during wound progression in the presence of hypoperfusion. Hydrogen has been reported to alleviate injury triggered by ischaemia/reperfusion and burns in various organs by selectively quenc...