burns are injuries which may require long hospitalization and may result in important impairment and disability. burn injuries are still common especially in developing countries. assessment of the epidemiology of burns is very important for introduction of preventive methods. this study was conducted in yazd to assess and describe the epidemiology of burns including its main causes, and its de...

Obtained sequences were aligned and analyzed by using Bioedit software (Ibis Biosciences, Carlsbad, CA, USA) and ClustalW version 2.0.10 (www.ebi.ac.uk/clustalw). DAMBE (http://dambe.bio.uottawa. ca/dambe.asp) and MEGA (www. megasoftware.net) software were used to obtain similarity percentages among analyzed sequences. To characterize Rickettsia spp., we used nucleotide sequence identity to ref...

Mediterranean spotted fever (MSF) is widely prevalent in many endemic regions in Bulgaria. The disease is still not quite thoroughly studied as to some aspects of its pathogenesis and especially to issues that concern the crucial signals for apoptosis in the target microvascular endothelial cells. To study the expression of Bcl-2 family proteins and Caspase-3 in the dermal capillary endothelial...

OBJECTIVES Injectable Bromelain Solution (IBS) is a modified investigational derivate of the medical grade bromelain-debriding pharmaceutical agent (NexoBrid) studied and approved for a rapid (four-hour single application), eschar-specific, deep burn debridement. We conducted an ex vivo study to determine the ability of IBS to dissolve-disrupt (enzymatic fasciotomy) Dupuytren's cords. MATERIA...

OBJECTIVE To compare the efficacy of dapsone, diphenhydramine, colchicine, and intralesional triamcinolone in the treatment of brown spider bites. We used a purified venom that reproducibly produces a large eschar. To mimic real-life circumstances, all agents were administered following a 2-hour delay after envenomation. The animals were evaluated for the presence of coagulopathy to determine i...

BACKGROUND Rickettsia sibirica mongolotimonae has been found in Hyalomma ticks in Inner Mongolia (in China) and Niger and in humans in France and South Africa. To date, only 3 cases of human infection have been reported. METHODS Patients received a diagnosis of R. sibirica mongolotimonae infection on the basis of culture and/or PCR results plus serological test results. RESULTS From January...