THE terms 'burns dressing' and 'analgesia', as they are understood in the Mclndoe Burns Unit at East Grinstead, will first be defined. Methoxyflurane as an analgesic for burns dressings will then be discussed. The term 'burns dressing' may mean: (1) Debridement and cleansing of the burn wound on admission, together with intravenous cannulation and urethral catheterization. (2) Removal of old dr...

This clinical trial aimed to evaluate the efficacy and safety of a novel wound dressing composed of hyaluronic acid (HA) and collagen (Col) containing epidermal growth factor (EGF), referred to as EGF-wound dressing. EGF-wound dressing was prepared by freeze-drying a mixed aqueous solution of high-molecular-weight HA, low-molecular-weight HA and heat-denatured Col containing EGF. EGF-wound dres...

Over the last 50 years, the evolution of burn treatment has led to a major decrease in mortality. Recently, survival in children has improved to such an extent that the survival rate in children with burns involving 100% total body surface area (TBSA) is 50% [1]. Major advances have been made in early resuscitation, respiratory care, the treatment of inhalation injury, control of infection, mod...

INTRODUCTION Burn wounds are a significant cause of morbidity and mortality, and improved outcomes are demonstrated with early closure of both primary burn wounds and skin donor sites. Thus, technology that decreases the healing time of burns and donor sites would be potentially lifesaving. We present the results of a single-center, prospective, double-blinded, randomized controlled trial to ev...

Accelerating the healing process and reducing pain during healing are beneficial for the following reasons: faster return to work, lower risk of wound infection, improved quality of life, and possibly reduced need for analgesia. This clinical study assessed the effectiveness of a new oxygen-diffusion dressing (OxyBand; Oxyband Technologies, St. Louis, MO) compared with standard Xeroform gauze d...

Conventional management of partial-thickness burn wounds includes the use of paraffin gauze dressing, frequently with topical silver-based antibacterial creams. Some creams form an overlying slough that renders wound assessment difficult and are painful upon application. An alternative to conventional management, moist exposed burn ointment (MEBO), has been proposed as a topical agent that may ...

The antibiotic-resistant bacteria are a major concern to wound care because of their ability to resist many of the antibiotics used today to treat infections. Consequently, other antimicrobials, in particular ionic silver, are considered ideal topical agents for effectively helping to manage and prevent local infections. Little is known about the antimicrobial efficacy of ionic silver on antibi...

A new bio restorable hybrid burn dressing which combines a synthetic porous top layer with a spongy collagen sub layer was developed and studied. The top layer contained the antibiotic drug gentamicin for controlled release to the wound site. Our investigation focused on the effects of gamma-irradiation sterilization (10, 25, 35 and 50 kGy) on the antibacterial efficacy and on the mechanical an...