In order to study the temperature change trend of surrounding geotechnical soil during operation and thermal recovery medium-deep geothermal buried pipe influence on operational stability vertical after recovery. Based data geological stratum in Guanzhong area actual engineering application heating system Xi’an New Area, law heat exchanger is simulated analyzed by FLUENT software. The results s...

The relationship between receptor number and agonist-induced intracellular responses has been well studied in receptors coupled to adenylate cyclase; however, for receptors coupled to phospholipase C (PLC), very little is known about the effect of receptor number on receptor-mediated processes. To explore this issue, we investigated the effect of the number of receptors for gastrin-releasing pe...

Gastrin-releasing peptide (GRP) causes multiple effects in humans by activating a specific heptaspanning receptor. Within the gastrointestinal tract, GRP receptors (GRP-R) are not normally expressed by mucosal epithelial cells except for those lining the gastric antrum. In contrast, recent studies have shown that up to 40% of resected colon cancers aberrantly express this receptor. This is impo...

Mammalian Gastrin Releasing Peptide (GRP) has a widespread distribution and multiple stimulating effects on metabolism, release of regulatory peptides, gastrointestinal and pancreatic secretions, and behaviour. GRP is a potent mitogen for a number of tumor types including colon and lung. Although GRP is known to stimulate the growth of renal tumors, little is known of its synthesis, distributio...

Gastrin-releasing peptide (GRP) has been reported to be implicated in the pathogenesis of inflammatory disorders. The migration and proliferation of vascular smooth muscle cells (VSMCs) are key components of vascular inflammation that leads to the development of atherosclerosis. The present study aimed to investigate the molecular effect of GRP on VSMC proliferation and migration. We report tha...

The backfill quality of a pipeline has an important influence on operation. When loose is used, the may be damaged after short term In this study, numerical simulation analysis buried pipes was carried out under three conditions: around pipe, dense backfill, and controlled low strength materials (CLSM) backfill. effects narrow trench backfilling using CLSM force deformation pipelines were studi...

Buried pipeline leakage will affect the thermal characteristics of soil environment, leading to a poor environment. In addition, natural gas possibly produces an explosion and subsequent fire, which has fatal harm. Sustainable detection underground leaks is significant part current research. this study, method for leak buried PE pipelines based on sound source investigated. The simulation softw...

Bombesin (BN) interacts with two mammalian receptor subtypes termed gastrin-releasing peptide (GRP)-preferring (GRP-R) and neuromedin B (NMB)-preferring (NMB-R) that may mediate the satiety action of BN. We examined the feeding behavior of mice that were deficient in the GRP-R (GRP-R KO) to assess the overall contribution of this receptor subtype in the feeding actions of BN-related peptides. G...