High energy irradiation to the hydrogen bonded system is important in relevance with the initial process of DNA and enzyme damages. In the present study, the effects of radiation to catalytic triad have been investigated by means of direct ab-initio molecular dynamics (AIMD) calculation. As a model of the catalytic triad, Ser-His-Glu residue, which is one of the important enzymes in the acylati...

Preface This is a report on the author's research initiated during the stay in GG ottingen in 1987/88 and continued over the past few years. The question posed at the very beginning was simple: to identify the area where we can still apply the classical limit theory for sums and maxima of independent random variables. Existence of asymptotic independent representations became a natural frame fo...