Previously, we found that KTH-13 isolated from the butanol fraction of Cordyceps bassiana (Cb-BF) displayed anti-cancer activity. To improve its antiproliferative activity and production yield, we employed a total synthetic approach and derivatized KTH-13 to obtain chemical analogs. In this study, one KTH-13 derivative, 4-(tert-butyl)-2,6-bis(1-phenylethyl)phenol (KTH-13-t-Bu), was selected to ...

electronic effects were investigated on the singlet–triplet energy gaps of divalent unsaturated seven- membered ring r2c6h6m (m=c, si, ge, sn, pb, r= –h, -ch3, i-pr , t-bu) at b3lyp/6-311++g** level. all the triplet states of r2c6h6c were more stable than the related the singlet states while all the singlet states of r2c6h6m (m= si, ge, sn, pb, r= –h, -ch3, i-pr , t-bu) were more stable than th...

The steady sta te photolysis of 5-bromouracil (BU) in aqueous solution has been studied as a function of wavelength, pH , tem perature, and hydrogen-donor concentration. U nder all conditions studied, the prim ary reaction is shown to be C-Br bond cleavage followed by abstraction from the hydrogen-donor to give uracil and H B r. A t pH > 12 further products are formed. In deoxygenated aqueous s...

BACKGROUND Buruli ulcer (BU) is a necrotizing bacterial infection of skin, subcutaneous tissue and bone caused by Mycobacterium ulcerans. Although the functional impairment caused by BU results in severe suffering and in socio-economic problems, the disease remains largely neglected in Africa. The province of Bas-Congo in Democratic Republic of Congo contains one of the most important BU foci o...

Reactions of the dianion [Te((t)BuN)P(μ-N(t)Bu)2P(N(t)Bu)Te](2-) with I2 or [Cp*RhCl2]2 unexpectedly produced complexes of the novel spirocyclic Te5 dianion [{(t)BuN(Te)P(μ-N(t)Bu)2P(Te)N(t)Bu}2μ-Te](2-), which is N,N'-coordinated to two Na(+) ions in the disodium derivative and adopts a Te,Te',Te''-bonding mode in the Cp*Rh complex.

This paper entails an in-depth study of the system bu er size requirements for parallel scienti c applications that communicate regularly with four or six neighbors. The goal of this study is to address two major issues: (1) for future system designs, which system features signi cantly impact the system bu er size requirements and (2) for systems where users can set the system bu er size (e.g.,...

Özet. Statik kod analizi yazılım kaynak kodunun kalite, güvenlik ve güvenilirlik açısından analiz edildiği bir yazılım doğrulama metodudur. Diğer doğrulama faaliyetlerinden farklı olarak, statik analiz otomatize edilebilmekte; bu sayede yazılımın koşmasına gerek kalmadan, ya da özel test durumları oluşturulmadan uygulanabilmektedir. Çeşitli metrikler kullanılarak yazılımların değerlendirilmesi ...

To investigate how top-down (TD) and bottom-up (BU) information is weighted in the guidance of human search behavior, we manipulated the proportions of BU and TD components in a saliency-based model. The model is biologically plausible and implements an artificial retina and a neuronal population code. The BU component is based on feature-contrast. The TD component is defined by a feature-templ...

Locations Hai Zhou1, D.F. Wong1, I-Min Liu2, and Adnan Aziz2 1 Department of Computer Sciences, University of Texas, Austin, TX 78712 2 Department of Electrical and Computer Engineering, University of Texas, Austin, TX 78712 Abstract During the routing of global interconnects, macro blocks form useful routing regions which allow wires to go through but forbid bu ers to be inserted. They give re...

Özet. NATO güçleri 2002 yılından beri Amerika’nın Afganistan üzerinde başlatmış olduğu bölgede kalıcı barışı sağlama amaçlı mücadelesine destek vermektedir. Bölgede devam eden mücadele öncelikli olarak her ne kadar asker gücü ile devam ettirilse de arka planda karar ve destek verme amaçlı çalışan bir çok yazılım sistemi bulunmaktadır. Bu yazılım sistemleri farklı zamanlarda farklı taraflar tara...