INTRODUCTION Bovine tuberculosis (bTB) is a chronic, zoonotic, multi-species disease of cattle caused by Mycobacterium bovis. In developed countries, effective surveillance and enforcement of regulations on bTB control resulted in significant reduction of infections in cattle and hence, humans. However, in developing countries, weak surveillance systems affect accurate and timely reporting of b...

Low-power design has gained much attention recently, especially for computing on batterypowered equipments. Reducing BTB (branch target buffer) accesses is an effective way to reduce processor power consumption, since BTB consumes a significant portion of power in a processor. In this paper, we propose two approaches to reduce BTB accesses. The first approach expects the distance of every two d...

Changes in host diversity have been postulated to influence the risk of infectious diseases, including both dilution and amplification effects. The dilution effect refers to a negative relationship between biodiversity and disease risk, whereas the amplification effect occurs when biodiversity increases disease risk. We tested these effects with an influential disease, bovine tuberculosis (BTB)...

The evolutionarily conserved BTB/POZ domain from the promyelocytic leukemia zinc finger (PLZF) oncoprotein mediates transcriptional repression through the recruitment of corepressor proteins containing histone deacetylases in acute promyelocytic leukemia. We have determined the 2.0 A crystal structure of the BTB/POZ domain from PLZF (PLZF-BTB/POZ), and have carried out biochemical analysis of P...

CGMT can exert significant influence on the design and implementation of branch prediction. In this paper, the design of several typical branch predictors such as bimodel, GShare and McFarling is examined and branch prediction performance is improved by making some decisions with the help of TPC-W benchmark concerning whether to share some data structures among multiple threads or not. For a ty...

The BTB/POZ (BTB) domain is an approximately 120 residue sequence that is conserved at the N-terminus of many proteins in both vertebrates and invertebrates. We found that the protein encoded by a lethal allele of the Drosophila modifier of mdg4 [mod(mdg4)] gene has two mutated residues in its BTB domain. The identities of the residues at the positions of these mutations are highly conserved in...

Branch target buffers (BTBs) are caches in which branch information is stored that is used for branch prediction by the fetch stage of the instruction pipeline. A typical BTB requires a few kbyte of storage which makes it rather large and, because it is accessed every cycle, rather power consuming. Partial resolution has in the past been proposed to reduce the size of a BTB. A partial resolutio...

A sensitive and efficient colorimetric method was optimized for detection of esterase enzymes produced by endophytic fungi for development of High-Throughput Screening (HTS). The fungi were isolated and obtained previously from plant species of Cerrado and Atlantic Forest located in areas of environmental preservation in the State of Sao Paulo / Brazil, as part of the project "Chemical and biol...

MODIFICATION OF CLAYS WITH IONIC LIQUIDS FOR POLYMER NANOCOMPOSITES by Neung Hyun Kim In attempts to prepare nanofillers with enhanced compatibility with a polymer matrix, cationic and anionic clays susceptible to exchange of their interlamellar ions with a variety of other cations or anions, were selected. In order to treat cationic clay, montmorillonite, which contains sodium ions as interlay...

Human and livestock diseases can be difficult to control where infection persists in wildlife populations. Control of bovine tuberculosis (bTB) in British cattle is complicated by the maintenance of Mycobacterium bovis (the causative agent of bTB) in badgers, acting as reservoirs of infection. Although over 20 000 badgers were culled to control bTB between 1975 and 1997, the incidence of bTB in...