Elderly HIV-infected patients may present particularities on both disease evolution and morbidity, as compared to younger patients. Moreover, elderly patients are more likely to take numerous medications due to their agerelated condition. VISAGE is a French multidisciplinary study group focusing on elderly HIV-infected patients in order to evaluate and improve their therapeutic care. Our study ...

Agilent Bond Elut C18 gave the best results is this effective application of derivatizing aliphatic and biogenic amines on SPE versus solution derivatization. Published by Springer. Forensics and toxicology Development and validation of a gas chromatography-mass spectrometry method for the simultaneous determination of buprenorphine, flunitrazepam and their metabolites in rat plasma: applicatio...

The role of inhaled iloprost should be suspected in cases of gastro-intestinal haemorrhage in patients suffering from pulmonary hypertension (PH) receiving this treatment, and the way the drug is administered should possibly be changed. Clinical, functional and haemodynamic deterioration of systemic scleroderma-PH in a 73-year-old Caucasian woman without any other past medical history, led to t...

To the Editor: An 82-year-old man was hospitalized with delirium at the University Hospital La Milétrie in February 2005. His medical history included giant cell arteritis diagnosed 9 years before and still treated with corticosteroids (prednisolone 4 mg/d). Treatment with fentanyl (25-mg patch) and codeine (up to 2,400 mg/d) was started because of refractory sciatic pain. His medications also ...

BACKGROUND Pain management is a high priority for patients with rheumatoid arthritis (RA). Muscle relaxants include drugs that reduce muscle spasm (for example benzodiazepines such as diazepam (Valium), alprazolam (Xanax), lorazepam (Ativan) and non-benzodiazepines such as metaxalone (Skelaxin) or a combination of paracetamol and orphenadrine (Muscol)) and drugs that prevent increased muscle to...

Clopidogrel, an adenosine biphosphate receptor antagonist, inhibits platelet aggregation and is widely used to prevent thrombotic complications of atherosclerosis or after percutaneous coronary stent placement. Various studies have shown that clopidogrel is as safe as aspirin and better tolerated than ticlopidine.1,2 The most common adverse effects are gastrointestinal discomfort, exanthema, an...