abstract breast cancer is one of the major health problems of the eastern world. regardless of the survival rate improvement with progression in screening and adjuvant systemic therapies, still one – third of the patients with primary breast cancer have recurrence of micro metastasis after 10 years.  it is important to discover a reliable biomarker for detection of breast cancer. the underlying...

introduction: breast cancer is one of the provalent cancers in the world. this cancer as well as other solid tumors, in the course of its development has phases in this order: epithelial dysplasia, carcinoma insitu, invassiveness and metastasis. breast cancer diagnosis is generally made with pathology methods. in this survey, measuring angiostatin (which is one of the most important and potent...

background and objective:determination of her2 gene is crucial in breast carcinoma management and prognosis, as her2 alterations are linked to a shorter disease-free period, overall survival and resistance to tamoxifen anti-estrogen therapy and other chemotherapy regimens, regardless of the nodal or hormone receptor status. this study aimed to estimate her2 gene status of infiltrative mammary c...

Breast cancer, which is an important public health problem worldwide, one of the deadliest cancers in women. This study aims to classify open-access breast cancer data and identify risk factors with Stochastic Gradient Boosting Method. The dataset was used construct a classification model study. disease. Balanced accuracy, sensitivity, specificity, positive/negative predictive

background: embarrassment and shame of visiting a doctor for a breast disease are among psychosocial factors that potentially contribute to delay in seeking medical advice. the purpose of this study is to review the published literature to determine if embarrassment regarding breast examination, diagnosis and treatment is associated with patient delay. methods: we searched pubmed with the follo...

background: breast cancer is the most common malignancy among women. it is estimated that 1 in 10 women worldwide is affected by breast cancer during their lifetime. in 5 to 10% of breast cancer patients, the disease results from a hereditary predisposition, which can be attributable to mutations in either of two tumor suppressor genes, brca1 and brca2 to a large extent. brca2 6174delt mutation...

breast conservation surgery combined with radiation therapy is now an accepted option for the treatment of early breast cancer. so we decided to evaluate the results of such treatment in our first group of patients treated by this method. from 1992 to 1996 , one hundred patients with stage i and ii breast cancer treated with breast conservative surgery (lumpectomy or quadrantectomy). were irrad...

background: contralateral axillary metastasis (cam) is a rare entity in patients with breast cancer which can occur during the primary breast cancer or its follow-up. different treatment modalities include surgery, radiotherapy, and chemotherapy, but there is no agreement on them. in our review, we found 12 series with available data, 82 patients with synchronous or metachronous contralateral a...